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BMH-21 | RNA Polymerase I inhibitor
From $52.00BMH-21 (896705-16-1) is a planar heterocyclic DNA intercalator that inhibits RNA polymerase I (Pol I), IC50 = 0.6 µM in U2OS cells, but not Pols II or […]
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CBL0137 | Inhibitor of the histone chaperone FACT
From $80.00CBL0137 (1197996-80-7) is an anticancer agent that activates p53 and suppresses NF-kB via trapping of the FACT (facilitates chromatin transcription) complex, an important histone chaperone that mediates nucleosome […]
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Cytochalasin D | Disrupts actin filaments
From $68.00CAS:22144-77-0Catalog Number:10-2071Activity:Disrupts actin filamentsChemical Name:(7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,17-dioneMolecular Weight:507.63Molecular Formula:C30H37NO6Solubility:Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 5 mg/ml).Physical Properties:White solidPurity:98% by TLCStorage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
DMOG | Inhibits prolyl hydroxylase domain-containing proteins
From $60.00CAS:89464-63-1Catalog Number:10-2371Activity:Inhibits prolyl hydroxylase domain-containing proteinsAlternate Names:DimethyloxalylglycineChemical Name:N-(2-Methoxy-2-oxoacetyl)glycine methyl esterMolecular Weight:175.14Molecular Formula:C6H9NO5Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:Off-white solidPurity:99% by TLC
NMR (Conforms)Storage Temperature:-20°CProtect from lightStability:Stable for 2 years from date of purchase as supplied. Solutions are not stable. Solutions must be made fresh and used within 1 working day.Shipping Code:RT -
EX-527 | SIRT1 inhibitor
From $40.00CAS:49843-98-3Catalog Number:10-1083Activity:SIRT1 inhibitorChemical Name:6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-xarboxamide (racemic)Molecular Weight:248.71Molecular Formula:C13H13ClN2OSolubility:Soluble in DMSO (up to 18 mg/ml) or in Ethanol (up to 10 mg/ml).Physical Properties:Light yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 monthsShipping Code:RT