Innate Immune System Activation

  • NVS-STG2 | Molecular glue STING agonist

    CAS:
    3030588-01-0
    Catalog Number:
    10-4134
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  • Resiquimod | TLR7/8 agonist / Immune adjuvant

    CAS:
    144875-48-9
    Catalog Number:
    10-2733
    Activity:
    TLR7/8 agonist / Immune adjuvant
    Chemical Name:
    1-[4-Amino-2-ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
    Alternate Names:
    R848
    Molecular Weight:
    314.39
    Molecular Formula:
    C17H22N4O2
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    >98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $65.00
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  • SR-717 | STING agonist

    CAS:
    2375421-09-1
    Catalog Number:
    10-4850
    Activity:
    STING agonist
    Chemical Names:
    Lithium 2-(6-(1H-Imidazol-1-yl)pyridazine-3-carboxamido)-4,5-difluorobenzoate
    Molecular Weight:
    381.27
    Molecular Formula:
    C15H8F2N5O3·Li
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month1.
    Shipping Code:
    RT
    From $80.00
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  • Vesatolimod | TLR7 agonist/antiviral

    CAS:
    1228585-88-3
    Catalog Number:
    10-4921
    Activity:
    TLR7 agonist
    Chemical Names:
    4-Amino-2-butoxy-8-[[3-(pyrrolidine-1-ylmethyl)phenyl]methyl]-5,7-dihydropteridin-6-one
    Alternate Name:
    GS-9620
    Molecular Weight:
    410.52
    Molecular Formula:
    C22H30N6O2
    Solubility:
    Soluble in DMSO (10 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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