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Tumor Microenvironment

  • Indoximod | IDO modulator / tryptophan mimetic

    CAS:
    110117-83-4
    Catalog Number:
    10-4569
    Activity:
    IDO modulator / tryptophan mimetic
    Chemical Name:
    1-Methyl-D-tryptophan
    Molecular Weight:
    218.25
    Molecular Formula:
    C12H14N2O2
    Solubility:
    Soluble in DMSO (greater than 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    >98%
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $35.00
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  • IPI-549 | Selective PI3Kgamma inhibitor / Immuno-oncology agent

    CAS:
    1693758-51-8
    Catalog Number:
    10-4827
    Activity:
    Selective PI3K-gamma inhibitor / Immuno-oncology agent
    Chemical Name:
    (S)-2-Amino-N-[1-[8-[2-(1-methylpyrazol-4-yl)ethynyl]-1-oxo-2-phenylisoquinolin-3-yl]ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide; Eganelisib
    Molecular Weight:
    528.58
    Molecular Formula:
    C30H24N8O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • KC7F2 | HIF-1α inhibitor

    CAS:
    927822-86-4
    Catalog Number:
    10-4714
    Activity:
    HIF-1alpha inhibitor
    Chemical Name:
    N,N’-(Dithiodi-2,1-ethanediyl)bis[2,5-dichlorobenzenesulfonamide
    Molecular Weight:
    570.38
    Molecular Formula:
    C16H16Cl4N2O4S4
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $60.00
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  • Leflunomide | Immunosuppressant

    CAS:
    75706-12-6
    Catalog Number:
    10-2369
    Activity:
    Immunosuppressant
    Alternate Names:
    RS-34821
    Chemical Name:
    5-Methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide
    Molecular Weight:
    270.21
    Molecular Formula:
    C12H9F3N2O2
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Linrodostat | IDO1 inhibitor

    CAS:
    1923833-60-6
    Catalog Number:
    10-4473
    View Product This product has multiple variants. The options may be chosen on the product page
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