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Tumor Microenvironment

  • Panobinostat | HDAC inhibitor

    CAS:
    404950-80-7
    Catalog Number:
    10-2157
    Activity:
    HDAC inhibitor
    Alternate Names:
    LBH-589
    Chemical Name:
    (E)-N-Hydroxy-3-(4-((2-(2-methyl-1H-indol-3-yl)ethylamino)methyl)phenyl)acrylamide
    Molecular Weight:
    349.44
    Molecular Formula:
    C21H23N3O2
    Solubility:
    Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $40.00
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  • Pazopanib chemical structure Focus Biomolecules

    Pazopanib | Multi-receptor tyrosine kinase inhibitor

    CAS:
    444731-52-6
    Catalog Number:
    10-2158
    View Product This product has multiple variants. The options may be chosen on the product page

  • Pexidartinib | CSF1R inhibitor

    CAS:
    1029044-16-3
    Catalog Number:
    10-4829
    Activity:
    CSF1R inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    5-[(5-Chloro-1H-pyrrolo[2,3.b]pyridine-3-yl)methyl]-N-[[6-(trifluoromethyl)pyridin-3-yl]methyl]pyridin-2-amine
    Alternate Names:
    PLX3397
    Molecular Weight:
    417.81
    Molecular Formula:
    C20H15ClF3N5
    Solubility:
    Soluble in DMSO (up to at least 10 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $45.00
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  • PF-06840003 | IDO1 inhibitor

    CAS:
    198474-05-4
    Catalog Number:
    10-4498
    Activity:
    IDO1 inhibitor/Cancer immunotherapy enhancer
    Chemical Name:
    3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione
    Alternate Name:
    EOS200271
    Molecular Weight:
    232.21
    Molecular Formula:
    C12H9FN2O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • PFK15 | Phosphofructo-2-kinase (PFKFB3) inhibitor

    CAS:
    4382-63-2
    Catalog Number:
    10-4580
    Activity:
    PFKFB3 inhibitor
    Chemical Names:
    1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one
    Molecular Weight:
    260.29
    Molecular Formula:
    C17H12N2O
    Solubility:
    Soluble in DMSO (15 mg/ml); ethanol (5 mg/ml)
    Physical Properties:
    Tan solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
    View Product This product has multiple variants. The options may be chosen on the product page
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