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Tumor Microenvironment

  • Decitabine | DNA hypomethylation agent

    CAS:
    2353-33-5
    Catalog Number:
    10-2412
    Activity:
    DNA hypomethylation agent
    Alternate Names:
    NSC-127716
    Chemical Name:
    5-Aza-2′-deoxycytidine
    Molecular Weight:
    228.21
    Molecular Formula:
    C8H12N4O4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Water (up to 11 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • Defactinib | Potent FAK inhibitor

    CAS:
    1073154-85-4
    Catalog Number:
    10-4828
    Activity:
    Potent FAK inhibitor
    Chemical Name:
    N-Methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]aminl]benzamide
    Molecular Weight:
    510.50
    Molecular Formula:
    C20H21F3N8O3S
    Solubility:
    Soluble in DMSO (up to at least 25mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • DMB chemical structure

    DMB | Gasdermin D agonist/GLP-1 agonist

    CAS:
    281209-71-0
    Catalog Number:
    10-3975
    View Product This product has multiple variants. The options may be chosen on the product page

  • DMXAA | STING agonist

    CAS:
    117570-53-3
    Catalog Number:
    10-2676
    Activity:
    STING agonist
    Chemical Name:
    5,6-Dimethylxanthenone-4-acetic acid
    Alternate Names:
    ASA404; Vadimezan
    Molecular Weight:
    282.29
    Molecular Formula:
    C17H14O4
    Solubility:
    Soluble in DMSO (up to 5 mg/ml) or in DMF (up to 14 mg/ml with warming)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • DS18561882 | MTHFD2 inhibitor

    CAS:
    2227149-22-4
    Catalog Number:
    10-4188
    Activity:
    MTHFD2 inhibitor
    Chemical Names:
    N-[4-[8-[(3S)-3,4-Dimethylpiperazin-1-yl]-7-methyl-5-oxo-2,4-dihydro-1H-chromeno[3,4-c]pyridine-3-carbonyl]-2-(trifluoromethoxy)phenyl]methanesulfonamide
    Alternate Name:
    DS18
    Molecular Weight:
    608.63
    Molecular Formula:
    C28H31F3N4O6S
    Solubility:
    Soluble in DMSO (at least 40 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $100.00
    View Product This product has multiple variants. The options may be chosen on the product page
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