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Tumor Microenvironment

  • DMB chemical structure

    DMB | Gasdermin D agonist/GLP-1 agonist

    CAS:
    281209-71-0
    Catalog Number:
    10-3975
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  • DMXAA | STING agonist

    CAS:
    117570-53-3
    Catalog Number:
    10-2676
    Activity:
    STING agonist
    Chemical Name:
    5,6-Dimethylxanthenone-4-acetic acid
    Alternate Names:
    ASA404; Vadimezan
    Molecular Weight:
    282.29
    Molecular Formula:
    C17H14O4
    Solubility:
    Soluble in DMSO (up to 5 mg/ml) or in DMF (up to 14 mg/ml with warming)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • DS18561882 | MTHFD2 inhibitor

    CAS:
    2227149-22-4
    Catalog Number:
    10-4188
    Activity:
    MTHFD2 inhibitor
    Chemical Names:
    N-[4-[8-[(3S)-3,4-Dimethylpiperazin-1-yl]-7-methyl-5-oxo-2,4-dihydro-1H-chromeno[3,4-c]pyridine-3-carbonyl]-2-(trifluoromethoxy)phenyl]methanesulfonamide
    Alternate Name:
    DS18
    Molecular Weight:
    608.63
    Molecular Formula:
    C28H31F3N4O6S
    Solubility:
    Soluble in DMSO (at least 40 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $100.00
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  • Echinomycin | HIF-1alpha inhibitor

    CAS:
    512-64-1
    Catalog Number:
    10-2424
    Activity:
    HIF1α inhibitor
    Alternate Names:
    Quinomycin A; NSC-13502
    Molecular Weight:
    1101.26
    Molecular Formula:
    C51H64N12O12S2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml)
    Physical Properties:
    White to beige solid
    Purity:
    >97% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months
    Shipping Code:
    RT
    From $90.00
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  • Enasidenib | Inhibitor of IDH2

    CAS:
    1446502-11-9
    Catalog Number:
    10-4660
    Activity:
    Inhibitor of IDH2
    Chemical Name:
    2-Methyl-1-[[4-[6(trifluoromethyl)-2-pyridinyl]-6-[[2-(trifluoromethyl)-4-pyridinyl]amino]-1,3,5-triazin-2-yl]amino]-2-propanol
    Alternate Names:
    AG-221
    Molecular Weight:
    473.38
    Molecular Formula:
    C19H17F6N7O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98%
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
    View Product This product has multiple variants. The options may be chosen on the product page
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