Highly-Selective Kinase Inhibitor Library
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Afatinib | EGFR and HER2 inhibitor
From $45.00CAS:850140-72-6Catalog Number:10-4510Activity:EGFR and HER2 inhibitorChemical Name:N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4(dimethylamino)-2E-butenamideAlternate Names:BIBW2992Molecular Weight:485.94Molecular Formula:C24H25ClFN5O3Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).Physical Properties:Pale yellow solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
Alectinib | Potent and selective ALK inhibitor
From $60.00CAS:1256580-46-7Catalog Number:10-4793Activity:Potent and selective ALK inhibitorChemical Name:9-Ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrileAlternate Name:CH5424802Molecular Weight:482.62Molecular Formula:C30H34N4O2Solubility:Soluble in DMSO (up to 5 mg/ml with warming).Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions are not stable and should be prepared fresh daily.Shipping Code:RT -
Apilimod | IL-12 and 23/PIKfyve inhibitor
From $35.00CAS:541550-19-0Catalog Number:10-4970Activity:IL-12 and 23/PIKfyve inhibitorChemical Names:N-[(E)-(3-Methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine; STA5326Molecular Weight:418.50Molecular Formula:C23H26N6O2Solubility:Soluble in DMSO (>25 mg/ml)Physical Properties:White solidPurity:99% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
AR-A 014418 | GSK-3 inhibitor
From $50.00CAS:487021-52-3Catalog Number:10-1195Activity:GSK-3 inhibitorChemical Name:N-[(4-Methoxyphenyl)methyl]-N’-(5-nitro-2-thiazolyl)ureaMolecular Weight:308.32Molecular Formula:C12H12N4O4SSolubility:Soluble in DMSO (up to 30 mg/ml).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT -
AZ20 | ATR kinase inhibitor
From $55.00CAS:1233339-22-4Catalog Number:10-4675Activity:ATR kinase inhibitorChemical Name:4-{4-[(3R)-3-Methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl}-1H-indoleMolecular Weight:412.51Molecular Formula:C21H24N4O3SSolubility:Soluble in DMSO (up to 20 mg/ml).Physical Properties:Off-white solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT
