Autophagy
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Anle138b | Protein aggregation inhibitor
From $55.00CAS:882697-00-9Catalog Number:10-4945Activity:Protein aggregation inhibitorChemical Name:5-(1,3-Benzodioxol-5-yl)-3-(3-bromophenyl)-1H-pyrazoleMolecular Weight:343.18Molecular Formula:C16H11BrN2O2Solubility:Soluble in DMSO (up to 15 mg/ml with warming).Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
Itraconazole | Autophagy inducer / Inhibits glioblastoma growth
From $45.00CAS:84625-61-6Catalog Number:10-2033Activity:Autophagy inducer / Inhibits glioblastoma growthAlternate Names:Oriconazole; R51211Molecular Weight:705.63Molecular Formula:C35H36Cl2N8O4Solubility:Soluble in DMSO (up to 1.5 mg/ml with warming)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Nelfinavir mesylate | HIV protease inhibitor / Anticancer activity
From $60.00CAS:159989-65-8Catalog Number:10-3050Activity:HIV protease inhibtior / Anticancer activityChemical Name:(3S,4aS,8aS)-N-(1,1-Dimethylethyl)decahydro-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-(phenylthio)butyl]-3-isoquinolinecarboxamide methanesulfonateAlternate Name:AG-1343Molecular Weight:663.88Molecular Formula:C32H45N3O4S • CH3SO3HSolubility:Soluble in DMSO (up to 70 mg/ml).Physical Properties:White solidPurity:98% by HPLCNMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.Shipping Code:RT -
PF-543 HCl | Sphingosine kinase-1 inhibitor
From $75.00PF-543 (1706522-79-3) is a potent (IC50 = 2.0 nM) and selective (>100-fold over SphK2) reversible inhibitor of sphingosine kinase-1 (SphK1).1 It induced autophagy in head and neck squamous […]
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Salirasib | Ras inhibitor
From $35.00CAS:162520-00-5Catalog Number:10-1461Activity:Ras inhibitorChemical Name:trans-Farnesylthiosalicylic acidMolecular Weight:358.54Molecular Formula:C22H30O2SSolubility:Soluble in DMSO (up to 20 mg/ml) oe in Ethanol (up to 20 mg/ml)Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Kinases
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
