Cancer Cell Metabolism

  • Brequinar sodium | Dihydroorotate dehydrogenase inhibitor, antiviral

    CAS:
    96201-88-6
    Catalog Number:
    10-3965
    Activity:
    Dihydroorotate dehydrogenase inhibitor, antiviral
    Chemical Name:
    6-Fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquinoline-4-carboxylic acid sodium salt
    Alternate Name:
    DuP-785; NSC 368390
    Molecular Weight:
    397.35
    Molecular Formula:
    C23H14F2NO2•Na
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to 15 mg/ml with warming)
    Physical Properties:
    Off-white or white solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20° C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $60.00
  • Canagliflozin | SGLT2 inhibitor

    CAS:
    842133-18-0
    Catalog Number:
    10-3576
    Activity:
    SGLT2 inhibitor
    Chemical Names:
    (1S)-1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol;
    JNJ-24831754
    Molecular Weight:
    444.52
    Molecular Formula:
    C24H25FO5S
    Solubility:
    Soluble in DMSO (40 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
  • CB-839 | Glutaminase inhibitor

    CAS:
    1439399-58-2
    Catalog Number:
    10-4556
    Activity:
    Glutaminase inhibitor
    Chemical Name:
    2-(Pyridin-2-yl)-N-(5-(4-(6-(2-(3-(trifluoromethoxy)phenyl)acetamido)pyridazin-3-yl)butyl)-1,3,4-thiadiazol-2-yl)acetamide
    Molecular Weight:
    571.57
    Molecular Formula:
    C26H24F3N7O3S
    Solubility:
    Soluble in DMSO.
    Physical Properties:
    Pale yellow solid
    Purity:
    >97% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $55.00
  • CBR-5884 | PHGDH / serine biosynthesis inhibitor

    CAS:
    681159-27-3
    Catalog Number:
    10-1588
    Activity:
    PHGDH inhibitor/ Blocks serine biosynthesis
    Chemical Name:
    Ethyl-5-(furan-carboxamido)-3-methyl-4-thiocyanatothiophene-2-carboxylate
    Molecular Weight:
    336.39
    Molecular Formula:
    C14H12N2O4S2
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in DMF (up to 50 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
  • Cerulenin | Fatty acid synthase inhibitor

    CAS:
    17397-89-6
    Catalog Number:
    10-2062
    Activity:
    Fatty Acid Synthase inhibitor
    Chemical Name:
    2,3-Epoxy-4-oxo-7,10-dodecadienamide
    Molecular Weight:
    223.27
    Molecular Formula:
    C12H17NO3
    Solubility:
    Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $120.00
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