Cell Cycle Archives | Page 8 of 12

NVP-BEZ235 | PI3-K and mTOR inhibitor

CAS:

915019-65-7

Catalog Number:

10-2153

Activity:

PI 3-K and mTOR inhibitor

Chemical Name:

2-Methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile

Molecular Weight:

469.55

Molecular Formula:

C₃₀H₂₃N₅O

Solubility:

Soluble in DMSO (up to 1 mg/ml with warming) or in DMF (up to 10 mg/ml, dissolves slowly, requires heating to 75¡C).

Physical Properties:

White or off-white solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 1 month.

Shipping Code:

RT

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Palbociclib | CDK4/CDK6 inhibitor

CAS:

571190-30-2

Catalog Number:

10-4760

Activity:

CDK4/CDK6 inhibitor

Chemical Name:

6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-piperazin-1-yl)pyridine-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one

Alternate Names:

PD-332991

Molecular Weight:

447.53

Molecular Formula:

C₂₄H₂₉N₇O₂

Solubility:

Soluble in DMSO (up to 2 mg/ml with warming)

Physical Properties:

Yellow solid

Purity:

99% by HPLC/TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Shipping Code:

RT

From $50.00
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Pemetrexed 2Na | Multitargeted antifolate

CAS:

357166-29-1

Catalog Number:

10-2162

Activity:

Multi-targeted antifolate

Chemical Name:

N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, disodium salt

Molecular Weight:

597.49

Molecular Formula:

C₂₀H₁₉N₅O₆ • 2Na • 7H₂O

Solubility:

Soluble in Water (up to 100 mg/ml).

Physical Properties:

White solid

Purity:

98% by TLC and HPLC
NMR (Conforms)

Storage Temperature:

-20° (des.)

Stability:

Stable for 1 year as supplied. Solutions in distilled water may be stored at -20° for up to 31month.

Shipping Code:

RT

From $70.00
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PLX-4032 | BRAF inhibitor

CAS:

918504-65-1

Catalog Number:

10-2928

Activity:

BRAF inhibitor

Chemical Name:

N-[3-[[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide

Alternate Names:

Vemurafenib, R7204, Ro 51-85426

Molecular Weight:

489.92

Molecular Formula:

C₂₃H₁₈ClF₂N₃O₃S

Solubility:

Soluble in DMSO (up to 100 mg/ml)

Physical Properties:

White or off-white solid

Purity:

99% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $40.00
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Purvalanol A | CDK inhibitor

CAS:

212844-53-6

Catalog Number:

10-2868

Activity:

CDK Inhibitor

Chemical Name:

(2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol

Alternate Names:

NG-60

Molecular Weight:

388.89

Molecular Formula:

C₁₉H₂₅ClN₆O

Solubility:

Soluble in DMSO (up to 35 mg/ml)

Physical Properties:

Pale green solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

Shipping Code:

RT

From $50.00
Select options

Cell Cycle

NVP-BEZ235 | PI3-K and mTOR inhibitor

Palbociclib | CDK4/CDK6 inhibitor

Pemetrexed 2Na | Multitargeted antifolate

PLX-4032 | BRAF inhibitor

Purvalanol A | CDK inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Cell Cycle

NVP-BEZ235 | PI3-K and mTOR inhibitor

Palbociclib | CDK4/CDK6 inhibitor

Pemetrexed 2Na | Multitargeted antifolate

PLX-4032 | BRAF inhibitor

Purvalanol A | CDK inhibitor

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21