Cellular Stress

  • TASIN-1 | Induces Apoptosis in cells with APC truncations

    CAS:
    1678515-13-3
    Catalog Number:
    10-4890
    Activity:
    Induces apoptosis in cells with APC truncations
    Chemical Names:
    1-[1-(4-Methoxyphenyl)sulfonylpiperidin-4-yl]-4-methylpiperidine hydrochloride
    Molecular Weight:
    388.95
    Molecular Formula:
    C18H28N2O3S·HCl
    Solubility:
    Soluble in DMSO (20 mg/ml)
    Physical Properties:
    White to off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $70.00
  • Temozolomide | Autophagy inducer

    CAS:
    85622-93-1
    Catalog Number:
    10-2390
    Activity:
    Autophagy inducer
    Alternate Names:
    NSC-362856
    Chemical Name:
    8-Carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one
    Molecular Weight:
    194.15
    Molecular Formula:
    C6H6N6O2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $75.00
  • TIC10 | Mitochondrial caseinolytic protease P activator / Anticancer agent

    CAS:
    1616632-77-9
    Catalog Number:
    10-4090
    Activity:
    Mitochondrial caseinolytic protease P activator / Anticancer agent
    Chemical Name:
    7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one
    Alternate Name:
    ONC201
    Molecular Weight:
    386.49
    Molecular Formula:
    C24H26N4O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml with warming).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $55.00
  • Toyocamycin | Unfolded protein response (UPR) inhibitor

    CAS:
    606-58-6
    Catalog Number:
    10-2750
    Activity:
    Unfolded protein response (UPR) inhibitor
    Chemical Name:
    4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
    Alternate Names:
    7-Deaza-7-cyanoadenosine; NSC 63701; NSC 99843; Neuro 000027; Unamycin B; Vengicide
    Molecular Weight:
    291.26
    Molecular Formula:
    C12H13N5O4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $70.00
  • Tunicamycin | ER stress inducer

    CAS:
    11089-65-9
    Catalog Number:
    10-2111
    Activity:
    ER stress inducer
    Molecular Weight:
    840.0 (Avg)
    Molecular Formula:
    C38H62N4O16 (tun. B)
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $85.00
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