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Kinases

  • CZC-8004 | Pan-kinase inhibitor

    CAS:
    916603-07-1
    Catalog Number:
    10-3032
    Activity:
    Multi-kinase inhibitor; affinity ligand
    Chemical Name:
    N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenyl-2,4-[yrimidinediamine
    Molecular Weight:
    309.33
    Molecular Formula:
    C17H16FN5
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 2.5 mg/ml with warming)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $90.00
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  • Dabrafenib | B-Raf mutant inhibitor

    CAS:
    1195765-45-7
    Catalog Number:
    10-1569
    Activity:
    B-Raf mutant inhibitor
    Chemical Name:
    N-[3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-benzenesulfonamide
    Alternate Names:
    GSK2118436
    Molecular Weight:
    519.56
    Molecular Formula:
    C23H20F3N5O2S
    Solubility:
    Soluble in DMSO (up to 30 mg/ml with warming), or in Ethanol (up to 1 mg/ml with warming).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • Dacomitinib chemical structure

    Dacomitinib | pan-ErbB inhibitor

    CAS:
    1110813-31-4
    Catalog Number:
    10-5340
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  • Defactinib | Potent FAK inhibitor

    CAS:
    1073154-85-4
    Catalog Number:
    10-4828
    Activity:
    Potent FAK inhibitor
    Chemical Name:
    N-Methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]aminl]benzamide
    Molecular Weight:
    510.50
    Molecular Formula:
    C20H21F3N8O3S
    Solubility:
    Soluble in DMSO (up to at least 25mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • Dinaciclib chemical structure

    Dinaciclib | CDK inhibitor

    CAS:
    779353-01-4
    Catalog Number:
    10-4845
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