Kinases
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Crenolanib | PDGFR and FLT3 inhibitor
From $60.00CAS:670220-88-9Catalog Number:10-4782Activity:PDGFR and FLT3 inhibitorChemical Name:1-[2-[5-[(3-Methyloxetan-3-yl)methoxy]benzimidazole-1-yl]quinoline-8-yl]piperidin-4-amineAlternate Name:CP-868,596Molecular Weight:443.55Molecular Formula:C26H29N5O2Solubility:Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 10 mg/ml).Physical Properties:White solidPurity:>97% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.Shipping Code:RT -
Crizotinib | c-MET and ALK inhibitor
From $80.00CAS:877399-52-5Catalog Number:10-2626Activity:c-MET and ALK inhibitorChemical Name:3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamineAlternate Names:PF-02341066, PF-1066Molecular Weight:450.34Molecular Formula:C21H22Cl2FN5OSolubility:Soluble in DMSO (up to 25 mg/ml with warming) or in Ethanol (up to 25 mg/ml with warming)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
CUDC-101 | Dual HDAC and EGFR inhibitor
From $70.00CAS:1012054-59-9Catalog Number:10-2491Activity:Dual HDAC and EGFR inhibitorChemical Name:7-((4-((3-Ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamideMolecular Weight:434.49Molecular Formula:C24H26N4O4Solubility:Soluble in DMSO (up to 25 mg/ml)Physical Properties:White or off-white solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
CZC-8004 | Multi-kinase inhibitor
From $90.00CAS:916603-07-1Catalog Number:10-3032Activity:Multi-kinase inhibitor; affinity ligandChemical Name:N2-[4-(Aminomethyl)phenyl]-5-fluoro-N4-phenyl-2,4-[yrimidinediamineMolecular Weight:309.33Molecular Formula:C17H16FN5Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 2.5 mg/ml with warming)Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Dabrafenib | B-Raf mutant inhibitor
From $40.00CAS:1195765-45-7Catalog Number:10-1569Activity:B-Raf mutant inhibitorChemical Name:N-[3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-benzenesulfonamideAlternate Names:GSK2118436Molecular Weight:519.56Molecular Formula:C23H20F3N5O2SSolubility:Soluble in DMSO (up to 30 mg/ml with warming), or in Ethanol (up to 1 mg/ml with warming).Physical Properties:Off-white solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT
EXPLORE OTHER Cancer
- ADC warheads
- Angiogenesis
- Autophagy
- Cancer Cell Metabolism
- Cancer Stem Cells
- Cell Cycle
- Cellular Stress
- Chemotherapeutics
- Cytoskeleton
- DNA Damage/Repair
- Drug resistance
- Epigenetics
- Gene Regulation/Transcription
- Growth factors
- Immuno-oncology
- Metastasis
- Other Cancer
- p53 & Other Tumor Suppressors
- Programmed cell death
- Stem Cells
- Ubiquitin proteasome
