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Kinases

  • AG-1517 HCl Supplier | CAS 153436-54-5 | Focus Biomolecules

    AG-1517 HCl | EGFR kinase inhibitor

    CAS:
    153436-54-5
    Catalog Number:
    10-1377
    Activity:
    EGFR kinase inhibitor
    Alternate Names:
    PD153,053; SU-5271; Z-252868
    Chemical Name:
    4-(3-Bromoanilino)-6,7-dimethoxyquinazoline hydrochloride
    Molecular Weight:
    360.21
    Molecular Formula:
    C16H14BrN3O2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $70.00
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  • AG-490 | JAK2 inhibitor

    CAS:
    133550-30-8
    Catalog Number:
    10-1091
    Activity:
    JAK2 inhibitor
    Chemical Name:
    (E)-2-Cyano-3-(3,4-dihydrophenyl)-N-(phenylmethyl)-2-propenamide
    Molecular Weight:
    294.31
    Molecular Formula:
    C17H14N2O3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml), in DMF (up to 40 mg/ml), or in Ethanol (up to 10 mg/ml).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, DMF, or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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  • Alectinib | Potent and selective ALK inhibitor

    CAS:
    1256580-46-7
    Catalog Number:
    10-4793
    Activity:
    Potent and selective ALK inhibitor
    Chemical Name:
    9-Ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
    Alternate Name:
    CH5424802
    Molecular Weight:
    482.62
    Molecular Formula:
    C30H34N4O2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions are not stable and should be prepared fresh daily.
    Shipping Code:
    RT
    From $60.00
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  • Alisertib chemical structure

    Alisertib | Potent and selective inhibitor of Aurora A / Destabilizes Myc

    CAS:
    1028486-01-2
    Catalog Number:
    10-4124
    Activity:
    Potent and selective inhibitor of Aurora A / Destabilizes Myc
    Chemical Name:
    4-{[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino}-2-methoxybenzoic acid
    Alternate Names:
    MLN8237
    Molecular Weight:
    518.92
    Molecular Formula:
    C27H20ClFN4O4
    Solubility:
    Soluble in DMSO (up to 5 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $65.00
    View Product This product has multiple variants. The options may be chosen on the product page

  • Alpelisib | PI3K⍺ inhibitor

    CAS:
    1217486-61-7
    Catalog Number:
    10-4167
    View Product This product has multiple variants. The options may be chosen on the product page
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