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Kinases

  • Alectinib | Potent and selective ALK inhibitor

    CAS:
    1256580-46-7
    Catalog Number:
    10-4793
    Activity:
    Potent and selective ALK inhibitor
    Chemical Name:
    9-Ethyl-6,6-dimethyl-8-(4-morpholin-4-ylpiperidin-1-yl)-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
    Alternate Name:
    CH5424802
    Molecular Weight:
    482.62
    Molecular Formula:
    C30H34N4O2
    Solubility:
    Soluble in DMSO (up to 5 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions are not stable and should be prepared fresh daily.
    Shipping Code:
    RT
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  • Alisertib | Potent and selective inhibitor of Aurora A / Destabilizes Myc

    CAS:
    1028486-01-2
    Catalog Number:
    10-4124
    Activity:
    Potent and selective inhibitor of Aurora A / Destabilizes Myc
    Chemical Name:
    4-{[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino}-2-methoxybenzoic acid
    Alternate Names:
    MLN8237
    Molecular Weight:
    518.92
    Molecular Formula:
    C27H20ClFN4O4
    Solubility:
    Soluble in DMSO (up to 5 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • Apigenin | Protein kinase inhibitor

    CAS:
    520-36-5
    Catalog Number:
    10-1242
    Activity:
    Protein kinase inhibitor
    Alternate Names:
    4,5,7-Trihydroxyflavone
    Chemical Name:
    5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
    Molecular Weight:
    270.24
    Molecular Formula:
    C15H10O5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $36.00
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  • Axitinib | VEGFR kinase inhibitor

    CAS:
    319460-85-0
    Catalog Number:
    10-2118
    Activity:
    VEGFR kinase inhibitor
    Chemical Name:
    N-Methyl-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide
    Molecular Weight:
    386.47
    Molecular Formula:
    C22H18N4OS
    Solubility:
    Soluble in DMSO (up to 30 mg/ml)
    Physical Properties:
    White solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • AZ3146 | Mps1 kinase inhibitor

    CAS:
    1124329-14-1
    Catalog Number:
    10-4778
    Activity:
    Mps1 kinase inhibitor
    Chemical Name:
    9-Cyclopentyl-2-[2-methoxy-4-(1-methylpiperidine-4-yl)oxyanilino]-7-methylpurin-8-one
    Molecular Weight:
    452.56
    Molecular Formula:
    C24H32N6O3S2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to at least 25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $60.00
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Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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