Kinases Archives | Page 4 of 30 | Focus Biomolecules

AZD1152-HQPA | Aurora B kinase inhibitor

CAS:

722544-51-6

Catalog Number:

10-4804

Activity:

Aurora B kinase inhibitor

Chemical Name:

3-[[7-[3-[Ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide

Alternate Name:

Barasertib-HQPA; AZD2811

Molecular Weight:

507.56

Molecular Formula:

C₂₆H₃₀FN₇O₃

Solubility:

Soluble in DMSO (up to 15 mg/ml).

Physical Properties:

Yellow solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

Shipping Code:

RT

From $50.00
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AZD6244 | ERK inhibitor

CAS:

606143-52-6

Catalog Number:

10-4509

Activity:

ERK inhibitor

Alternate Names:

ARRY-142886, Selumetinib

Molecular Weight:

457.68

Molecular Formula:

C₁₇H₁₅BrClFN₄O₃

Solubility:

Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 2 mg/ml)

Physical Properties:

White solid

Purity:

99% by HPLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.

Shipping Code:

RT

From $40.00
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AZD7762 | Checkpoint kinase 1/2 inhibitor

CAS:

860352-01-8 (free base)

Catalog Number:

10-4771

Activity:

Checkpoint kinase 1/2 inhibitor

Chemical Name:

3-(Carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-piperidin-3-yl]thiophene-2-carboxamide hydrochloride

Molecular Weight:

398.88

Molecular Formula:

C₁₇H₁₉FN₄O₂S • HCl

Solubility:

Soluble in DMSO (up to at least 25 mg/ml).

Physical Properties:

Yellow or brown solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

Shipping Code:

RT

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AZD8055 | mTOR kinase inhibitor

CAS:

1009298-09-2

Catalog Number:

10-4816

Activity:

mTOR kinase inhibitor

Chemical Name:

(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol

Molecular Weight:

465.54

Molecular Formula:

C₂₅H₃₁N₅O₄

Solubility:

Soluble in DMSO (up to 30 mg/ml)

Physical Properties:

Yellow solid

Purity:

99% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

Shipping Code:

RT

From $45.00
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BI 2536 | Dual Plk/BRD4 inhibitor – Destabilizes Myc

CAS:

755038-02-9

Catalog Number:

10-4121

Activity:

Dual Plk/BRD4 inhibitor – Destabilizes Myc

Chemical Name:

4-[[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-7H-pteridin-2-yl]amino]-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide

Molecular Weight:

521.67

Molecular Formula:

C₂₈H₃₉N₇O₃

Solubility:

Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 25 mg/ml)

Physical Properties:

Off-white solid

Purity:

97% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $75.00
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Kinases

AZD1152-HQPA | Aurora B kinase inhibitor

AZD6244 | ERK inhibitor

AZD7762 | Checkpoint kinase 1/2 inhibitor

AZD8055 | mTOR kinase inhibitor

BI 2536 | Dual Plk/BRD4 inhibitor – Destabilizes Myc

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Kinases

AZD1152-HQPA | Aurora B kinase inhibitor

AZD6244 | ERK inhibitor

AZD7762 | Checkpoint kinase 1/2 inhibitor

AZD8055 | mTOR kinase inhibitor

BI 2536 | Dual Plk/BRD4 inhibitor – Destabilizes Myc

EXPLORE OTHER Cancer

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21