Programmed cell death

  • Spautin-1 | Inhibits autophagy by inhibiting USP 10 and 13

    CAS:
    1262888-28-7
    Catalog Number:
    10-1367
    Activity:
    Inhibits autophagy by inhibiting USP 10 and 13
    Chemical Name:
    6-Fluoro-N[(4-fluorophenyl)methyl]-4-quinazolinamine
    Molecular Weight:
    271.27
    Molecular Formula:
    C15H11F2N3
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $65.00
  • SR9243 | LXR inverse agonist

    CAS:
    1613028-81-1
    Catalog Number:
    10-4579
    Activity:
    LXR inverse agonist
    Chemical Name:
    N-[2-(3-Bromophenyl)ethyl]-2,4,6-trimethyl-N-[[3Õ-(methylsulfonyl)[1,1Õ-biphenyl]-4-yl]methyl]-benzenesulfonamide
    Molecular Weight:
    626.62
    Molecular Formula:
    C31H32BrNO4S2
    Solubility:
    Soluble in DMSO (greater than 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $45.00
  • SRS16-86 | Ferroptosis inhibitor

    CAS:
    1793052-96-6
    Catalog Number:
    10-4668
    Activity:
    Ferroptosis inhibitor
    Chemical Names:
    tert-Butyl 4-(1-adamantylamino)-3-(pyrimidin-5-ylmethylideneamino)benzoate
    Molecular Weight:
    432.57
    Molecular Formula:
    C26H32N4O2
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $69.00
  • Stattic | STAT3 inhibitor

    CAS:
    19983-44-9
    Catalog Number:
    10-2524
    Activity:
    STAT3 inhibitor
    Chemical Name:
    6-Nitrobenzo[b]thiophene 1,1-dioxide
    Molecular Weight:
    211.2
    Molecular Formula:
    C8H5NO4S
    Solubility:
    Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 1 mg/ml).
    Physical Properties:
    Light yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $45.00
  • Sulindac Sulfone | Modulates beta-catenin-mediated effects

    CAS:
    59864-04-9
    Catalog Number:
    10-1122
    Activity:
    Modulates beta-catenin-mediated effects
    Chemical Name:
    (Z)-5-Fluoro-2-methyl-1-[p-(methylsulfonyl)benzylidene]indene-3-acetic acid
    Molecular Weight:
    372.41
    Molecular Formula:
    C20H17FO4S
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    >98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week.
    Shipping Code:
    RT
    From $50.00
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