Programmed cell death Archives | Page 2 of 27

ABT-263 | Bcl-2 family inhibitor; Senolytic agent

CAS:

923564-51-6

Catalog Number:

10-3141

Activity:

Bcl-2 family inhibitor; Senolytic agent

Chemical Name:

4-[4-[[2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)- 3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]-benzamide

Alternate Name:

Navitoclax

Molecular Weight:

974.61

Molecular Formula:

C₄₇H₅₅ClF₃N₅O₆S₃

Solubility:

Soluble in DMSO (up to 25 mg/ml).

Physical Properties:

White solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.

Shipping Code:

RT

From $60.00
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ABT-737 | Senolytic Bcl2 inhibitor

CAS:

852808-04-9

Catalog Number:

10-3661

Activity:

Senolytic Bcl inhibitor

Chemical Names:

4-[4-[(4′-Chloro[1,1′-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]-benzamide

Molecular Weight:

813.43

Molecular Formula:

C₄₂H₄₅ClN₆O₅S₂

Solubility:

Soluble in DMSO (5 mg/ml)

Physical Properties:

Yellow solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $80.00
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Adapalene | Retinoid RARbeta, gamma agonist

CAS:

106685-40-9

Catalog Number:

10-1011

Activity:

Retinoid RARβ,γ agonist

Alternate Names:

CD271

Chemical Name:

6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthoic acid

Molecular Weight:

412.53

Molecular Formula:

C₂₈H₂₈O₃

Solubility:

Soluble in DMSO (up to 3 mg/ml) or in DMF (up to 6 mg/ml).

Physical Properties:

White solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

RT

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months

Shipping Code:

RT

From $30.00
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AG-1296 | PDGFR kinase inhibitor

CAS:

146535-11-7

Catalog Number:

10-1087

Activity:

PDGFR kinase inhibitor

Chemical Name:

6,7-Dimethoxy-3-phenylquinoxaline

Molecular Weight:

266.3

Molecular Formula:

C₁₆H₁₄N₂O₂

Solubility:

Soluble in DMSO.

Physical Properties:

Yellow solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $60.00
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Altretamine | Ferroptosis inducer

CAS:

645-05-6

Catalog Number:

10-5592

Activity:

Ferroptosis inducer/GPX4 inhibitor

Chemical Names:

N2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-triazine-2,4,6-triamine; 2,4,6-Tris(dimethylamino)-1,3,5-triazine

Alternate Name:

Hexamethylmelamine; NSC-13875

Molecular Weight:

210.29

Molecular Formula:

C₉H₁₈N₆

Solubility:

Soluble in DMSO (40 mg/ml)

Physical Properties:

White solid

Purity:

>98% TLC
NMR (Conforms)

Storage Temperature:

Room temperature

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $35.00
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