Atherosclerosis

  • 1G244 | DPP8/9 inhibitor

    CAS:
    847928-32-9
    Catalog Number:
    10-4584
    Activity:
    DPP8/9 inhibitor
    Chemical Names:
    (S)-2-Amino-4-{4-[bis-(4-fluorophenyl)-methyl]piperazin-1-yl}-1-(1,3-dihydro-isoindol-2-yl)-butane-1,4-dione
    Alternate Name:
    PTX-1210
    Molecular Weight:
    504.57
    Molecular Formula:
    C29H30F2N4O2
    Solubility:
    Soluble in DMSO (>20 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $70.00
  • 5alpha,6alpha-Epoxycholesterol | LXR ligand

    CAS:
    1250-95-9
    Catalog Number:
    10-4545
    Activity:
    LXR ligand
    Chemical Name:
    Cholestan-5α,6α-epoxy-3β-ol
    Molecular Weight:
    402.65
    Molecular Formula:
    C27H46O2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml) orin Ethanol (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $25.00
  • Atglistatin | ATGL inhibitor

    CAS:
    1469924-27-3
    Catalog Number:
    10-4598
    Activity:
    ATGL inhibitor
    Chemical Name:
    N’-[4’-(Dimethylamino)[1,1’-biphenyl]-3-yl]-N,N,-dimethylurea
    Molecular Weight:
    283.37
    Molecular Formula:
    C17H21N3O
    Solubility:
    Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 5 mg/ml with warming)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $60.00
  • Belnacasan | ICE/caspase-1 inhibitor

    CAS:
    273404-37-8
    Catalog Number:
    10-4399
    Activity:
    ICE/caspase-1 inhibitor
    Chemical Names:
    (S)-1-((S)-2-(4-Amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)-N-((2R,3S)-2-ethoxy-5-oxotetrahydrofuran-3-yl)pyrrolidine-2-carboxamide; VX-765
    Molecular Weight:
    508.99
    Molecular Formula:
    C24H33ClN4O6
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white to white solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
  • Bempedoic acid | ATP citrate lyase inhibitor

    Bempedoic acid (738606-46-7) is an inhibitor of ATP citrate lyase (ACL) and activator of AMPK used in the treatment of hypercholesterolemia.1,2 In vivo, the active molecule is […]

    From $45.00
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