Heart Failure

  • PKSI-527 | Selective plasma kallikrein inhibitor

    CAS:
    128837-71-8
    Catalog Number:
    10-2220
    Activity:
    Selective plasma kallikrein inhibitor
    Chemical Names:
    trans-4-Aminomethylcyclohexanecarbonyl-phenylalanyl-4-carboxymethylanilide
    Molecular Weight:
    474.01
    Molecular Formula:
    C25H31N3O4·HCl
    Solubility:
    Soluble in Water (5 mg/ml)
    Physical Properties:
    White solid
    Purity:
    97% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
  • Pyr3 | TRPC3 Channel blocker

    CAS:
    1160514-60-2
    Catalog Number:
    10-1077
    Activity:
    TRPC3 Channel blocker
    Chemical Name:
    1-[4-[(2,3,3-Trichloro-1-oxo-2-propen-1-yl)amino]phenyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid
    Molecular Weight:
    456.64
    Molecular Formula:
    C16H11Cl3F3N3O3
    Solubility:
    Soluble in DMSO (up to 40 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $310.00
  • Ro 13-6438 | PDE3 inhibitor

    CAS:
    70018-51-8
    Catalog Number:
    10-1056
    Activity:
    PDE3 inhibitor
    Chemical Name:
    (R)-6-Chloro-1,5-dihydro-3-methylimidazo[2,1-b]quinazolin-2-one
    Molecular Weight:
    235.67
    Molecular Formula:
    C11H10ClN3
    Solubility:
    Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 1 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
    Shipping Code:
    RT
    From $75.00
  • Tafamidis | Transthyretin stabilizer

    CAS:
    594839-88-0
    Catalog Number:
    10-3743
    Activity:
    Transthyretin stabilizer
    Chemical Name:
    2-(3,5-Dichlorophenyl)-6-benzoxazolecarboxylic acid
    Alternate Name:
    PF-06291826
    Molecular Weight:
    308.12
    Molecular Formula:
    C14H7Cl2NO3
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
  • Teprenone | HSP70 inducer

    CAS:
    6809-52-5
    Catalog Number:
    10-2262
    Activity:
    HSP70 inducer
    Alternate Names:
    Geranylgeranylacetone; GGA
    Chemical Name:
    6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one
    Molecular Weight:
    350.55
    Molecular Formula:
    C23H38O
    Solubility:
    Soluble in DMSO (up to 30 mg/ml).
    Physical Properties:
    Colorless oil
    Purity:
    >95% by GC
    NMR (Confirms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $50.00
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