p53

  • Pifithrin α | p53 inhibitor

    CAS:
    63208-82-2
    Catalog Number:
    10-2480
    Activity:
    p53 inhibitor
    Alternate Names:
    PFT-α
    Chemical Name:
    1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone á HBr
    Molecular Weight:
    367.31
    Molecular Formula:
    C16H18N2OS HBr
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
  • Pifithrin µ | Hsp70 inhibitor

    CAS:
    64984-31-2
    Catalog Number:
    10-1180
    Activity:
    Hsp70 inhibitor
    Alternate Names:
    PES, NSC-303580
    Chemical Name:
    2-Phenylethynesulfonamide
    Molecular Weight:
    181.21
    Molecular Formula:
    C8H7NO2S
    Solubility:
    Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
  • PRIMA-1(MET) | Reactivates mutant p53

    CAS:
    5291-32-7
    Catalog Number:
    10-4175
    Activity:
    Reactivates mutant p53
    Chemical Name:
    2-(Hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one
    Alternate Names:
    APR-246
    Molecular Weight:
    199.25
    Molecular Formula:
    C10H17NO3
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    White solid
    Purity:
    95%
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $50.00
  • RITA | p53 Activator

    CAS:
    213261-59-7
    Catalog Number:
    10-3385
    Activity:
    P53 Activator
    Chemical Names:
    5,5′-(2,5-Furandiyl)bis-2-thiophenemethanol;
    NSC 652287
    Molecular Weight:
    292.37
    Molecular Formula:
    C14H12O3S2
    Solubility:
    Soluble in DMSO (up to 20 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $70.00
  • SL-01 | p53/mdm2 inhibitor

    CAS:
    26049-94-5
    Catalog Number:
    10-1326
    Activity:
    p53/mdm2 inhibitor
    Alternate Names:
    ZPCK
    Chemical Name:
    N-Benzyloxycarbonyl-L-phenylalaninylchloromethyl ketone
    Molecular Weight:
    331.8
    Molecular Formula:
    C18H18ClNO3
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $30.00
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