Pattern recognition receptors

  • Allopregnanolone | GABA-A positive allosteric modulator

    CAS:
    516-54-1
    Catalog Number:
    10-3489
    Activity:
    GABA-A positive allosteric modulator
    Chemical Name:
    (3α,5α)-3-Hydroxy-pregnan-20-one
    Alternate Name:
    (3α,5α)-Tetrahydroprogesterone; 3-OH-DHP
    Molecular Weight:
    318.49
    Molecular Formula:
    C21H34O2
    Solubility:
    Soluble in DMSO (up to 32 mg/ml) or in Ethanol (up to 32 mg/ml)
    Physical Properties:
    White or off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20° (des.)
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $70.00
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  • FPS-ZM1 | RAGE receptor antagonist

    CAS:
    945714-67-0
    Catalog Number:
    10-4616
    Activity:
    RAGE receptor antagonist
    Chemical Name:
    4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide
    Molecular Weight:
    327.85
    Molecular Formula:
    C20H22ClNO
    Solubility:
    Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 20 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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  • Imiquimod | TLR7 Agonist

    CAS:
    99011-02-6
    Catalog Number:
    10-4230
    Alternate Name:
    R837
    Activity:
    TLR7 agonist
    Chemical Name:
    1-(2-Methylpropyl)imidazo[4,5-c]quinolin-4-amine
    Molecular Weight:
    240.30
    Molecular Formula:
    C14H16N4
    Solubility:
    Soluble in DMSO (2 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    >98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $30.00
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  • Loxoribine | TLR7 agonist

    CAS:
    121288-39-9
    Catalog Number:
    10-3780
    Activity:
    TLR7 agonist
    Chemical Name:
    7-Allyl-7,8-dihydro-8-oxoguanosine
    Alternate Name:
    RWJ-21757
    Molecular Weight:
    339.30
    Molecular Formula:
    C13H17N5O6
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    96% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • Motolimod | TLR8 agonist

    CAS:
    926927-61-9
    Catalog Number:
    10-4920
    Activity:
    TLR8 agonist/Cancer immunotherapy enhancer
    Alternate Name:
    VTX-2337
    Chemical Name:
    2-Amino-N,N-dipropyl-8-[4-(pyrrolidine-1-carbonyl)phenyl]-3H-1-benzapine-4-carboxamide
    Molecular Weight:
    458.61
    Molecular Formula:
    C28H34N4O2
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Off-white or pale yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $80.00
    View Product This product has multiple variants. The options may be chosen on the product page
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