Immunosuppressants
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6-Mercaptopurine | Purine antimetabolite and immunomodulator
From $25.00CAS:6112-76-1Catalog Number:10-4698Activity:Purine antimetabolite and immunomodulatorChemical Names:3,7-Dihydropurine-6-thione monohydrateAlternate Name:6-MPMolecular Weight:170.19Molecular Formula:C5H4N4S·H2OSolubility:Soluble in DMSO (>50 mg/ml); ethanol (5 mg/ml with warming)Physical Properties:Yellow solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:Room temperatureStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
6-Thioguanine | Anticancer agent / Downregulates DNMT1
From $30.00CAS:154-42-7Catalog Number:10-1282Activity:Anticancer agent / Downregulates DNMT1Chemical Name:2-Amino-6-mercaptopurineAlternate Names:6-TG; NSC 752, NSC 76504Molecular Weight:167.19Molecular Formula:C5H5N5SSolubility:Soluble in DMF (up to 1.5 mg/ml with warming)Physical Properties:Pale yellow solidPurity:96% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMF may be stored at -20°C for up to 1 month.Shipping Code:RT -
A77 1726 | DHODH inhibitor
From $45.00CAS:108605-62-5Catalog Number:10-1436Activity:DHODH inhibitorAlternate Names:TeriflunomideChemical Name:2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamideMolecular Weight:270.21Molecular Formula:C12H9F3N2O2Solubility:Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 5 mg/ml with warming).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Ascomycin | FKBP ligand/Immunosuppressant
From $35.00CAS:11011-38-4Catalog Number:10-2059Activity:FKBP ligand; immunosuppressantAlternate Names:FK-520, FR-900520Chemical Name:Fermentation product from Streptomyces hygroscopicusMolecular Weight:729.03Molecular Formula:C43H69NO12Solubility:Soluble in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml with warming).Physical Properties:White solidPurity:99% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
AX-024 | Inhibitor of T cell antigen receptor (TCR)-dependent T cell activation
From $90.00CAS:1704801-24-0Catalog Number:10-4895Activity:Inhibitor of T cell antigen receptor (TCR)-dependent T cell activationChemical Name:1-[[4-(4-Fluorophenyl)-6-methoxy-2H-chromen-3-yl]methyl]pyrrolidine hydrochlorideMolecular Weight:375.86Molecular Formula:C21H22FNO2•HClSolubility:Soluble in DMSO (up to at least 25 mg/ml with warming) or in Water (10 mg/ml with warming).Physical Properties:White solidPurity:98% by HPLCNMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.Shipping Code:RT
