Neurodegeneration

  • Tafamidis | Transthyretin stabilizer

    CAS:
    594839-88-0
    Catalog Number:
    10-3743
    Activity:
    Transthyretin stabilizer
    Chemical Name:
    2-(3,5-Dichlorophenyl)-6-benzoxazolecarboxylic acid
    Alternate Name:
    PF-06291826
    Molecular Weight:
    308.12
    Molecular Formula:
    C14H7Cl2NO3
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
  • Terguride | Dopamine D2 agonist

    CAS:
    37686-84-3
    Catalog Number:
    10-2308
    Activity:
    Dopamine D2 agonist
    Alternate Names:
    S(+)-Terguride
    Chemical Name:
    S(+)-N,N-Diethyl-N'([8α]-6-methylergolin-8-yl)urea
    Molecular Weight:
    340.47
    Molecular Formula:
    C20H28N4O
    Solubility:
    Soluble in DMSO or in Ethanol.
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $125.00
  • Tetrabenazine | VMAT2 inhibitor

    CAS:
    58-46-8
    Catalog Number:
    10-2672
    Activity:
    VMAT2 inhibitor
    Chemical Name:
    (3R,11bR)-rel-1,3,4,6,7,11b-Hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one
    Molecular Weight:
    317.43
    Molecular Formula:
    C19H27NO3
    Solubility:
    Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 9 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
    Shipping Code:
    RT
    From $30.00
  • Thiamet G | O-GlcNAcase antagonist

    CAS:
    1009816-48-1
    Catalog Number:
    10-2824
    Activity:
    O-GlcNAcase alpha 1 antagonist
    Chemical Name:
    (3aR,5R,6S,7R,7aR)-2-(Ethylamino)-3a,6,7,7a-tetrahydro-5-(hydroxymethyl)-5H-Pyrano[3,2-d]thiazole-6,7-diol
    Molecular Weight:
    248.30
    Molecular Formula:
    C9H16N2O4S
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $70.00
  • Tolcapone | COMT inhibitor / TTR aggregation inhibitor

    CAS:
    134308-13-7
    Catalog Number:
    10-3075
    Activity:
    COMT inhibitor / TTR aggregation inhibitor
    Chemical Name:
    (3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone
    Alternate Names:
    Ro 40-7592
    Molecular Weight:
    273.24
    Molecular Formula:
    C14H11NO5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $50.00
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