Neuroprotection

  • PF-4708671 dihydrochloride | S6K1 inhibitor

    CAS:
    125517-76-0 (free base)
    Catalog Number:
    10-4856
    Activity:
    S6K1 inhibitor
    Chemical Names:
    2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzimidazole dihydrochloride
    Molecular Weight:
    463.33
    Molecular Formula:
    C19H21F3N6·2HCl
    Solubility:
    Soluble in DMSO (at least 35 mg/ml); Water (at least 50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or water may be stored at -20°C for up to 1 month. Hygroscopic solid – protect from moisture.
    Shipping Code:
    RT
    From $40.00
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  • PI-103 | Potent inhibitor of PI3-kinase, mTOR, and DNA-PK

    CAS:
    371935-74-9
    Catalog Number:
    10-5406
    Activity:
    Potent inhibitor of PI3-kinase, mTOR and DNA-PK
    Chemical Name:

    3-[4-(4-Morpholinyl)pyrido[3’,2’:4,5]furo[3,2-d]pyrimidin-2-yl]-phenol

    Molecular Weight:
    348.36
    Molecular Formula:
    C19H16N4O3
    Solubility:
    Soluble in DMSO (up to 40 mg/ml)
    Physical Properties:
    White solid
    Purity:

    98% by TLC
    NMR (Conforms)

    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $60.00
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  • Pifithrin α | p53 inhibitor

    CAS:
    63208-82-2
    Catalog Number:
    10-2480
    Activity:
    p53 inhibitor
    Alternate Names:
    PFT-α
    Chemical Name:
    1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone á HBr
    Molecular Weight:
    367.31
    Molecular Formula:
    C16H18N2OS HBr
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • Pinacidil | Potassium channel opener

    CAS:
    85371-64-8
    Catalog Number:
    10-2856
    Activity:
    Potassium channel opener
    Chemical Name:
    (+/-)-N-Cyano-N’-4-pyridinyl-Nα-(1,2,2-trimethylpropyl)guanidine monohydrate
    Molecular Weight:
    263.34
    Molecular Formula:
    C13H19N5 • H2O
    Solubility:
    Soluble in DMSO (up to 25 mg/ml with warming) or in Ethanol (up to 25 mg/ml with warming).
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $30.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • PJ-34 HCl | PARP1/2 inhibitor

    CAS:
    344458-15-7
    Catalog Number:
    10-2395
    Activity:
    PARP1,2 inhibitor
    Chemical Name:
    N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-(N,N-dimethylamino)acetamide hydrochloride
    Molecular Weight:
    331.81
    Molecular Formula:
    C17H17N3O2
    Solubility:
    Soluble in DMSO (up to 30 mg/ml) or in Water (up to 20 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $56.00
    View Product This product has multiple variants. The options may be chosen on the product page
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