NASH/NAFLD
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BI01383298 | Citrate transporter inhibitor
From $50.00BI01383298 (2227549-00-8) is a potent, non-competitive, irreversible inhibitor of the human Na+-coupled citrate transporter (NaCT/SLC13A5/mINDY).1,2 IC50 = 49 nM in the presence of Li+ with preincubation […]
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DT-109 | Induces glutathione biosynthesis
From $35.00CAS:14857-82-0Catalog Number:10-5732Activity:Induces glutathione biosynthesisChemical Names:Glycyl-glycyl-L-leucine; Gly-Gly-Leu-OHMolecular Weight:245.28Molecular Formula:C10H19N3O4Solubility:Soluble in DMSO (25 mg/ml with warming); Water (25 mg/ml)Physical Properties:White solidPurity:>98% TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Firsocostat | Allosteric acetyl-CoA carboxylase inhibitor
From $75.00CAS:1434635-54-7Catalog Number:10-4699Activity:Allosteric ACC inhibitorChemical Names:2-[1-[(2R)-2-(2-Methoxyphenyl)-2-9oxan-4-yloxy)ethyl]-5-methyl-6-(1,3-oxazol-2-yl)-2,4-dioxothieno[2,3-d]pyrimidin-3-yl]-2-methylpropanoic acidAlternate Name:ND-630; NDI-010976; GS-0976Molecular Weight:569.63Molecular Formula:C28H31N3O8SSolubility:Soluble in DMSO (>25 mg/ml)Physical Properties:white solidPurity:98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
GSK620 | BD2 selective BET inhibitor
From $60.00GSK620 (2088410-46-0) is a BET inhibitor 220-fold more selective for BD2 over BD1 (pIC50 BD2 = 7.1; BD1 = 4.8).1 It ameliorated collagen-induced arthritis in a rat model […]
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Oltipraz | Nrf2 activator
From $39.00CAS:64224-21-1Catalog Number:10-2831Activity:Nrf2 activatorChemical Name:4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thioneMolecular Weight:226.34Molecular Formula:C8H6N2S3Solubility:Soluble in DMSO (up to 50 mg/ml).Physical Properties:Red solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT
