Apoptosis

  • MLN4924 | NEDD8 activating enzyme inhibitor

    CAS:
    905579-51-3
    Catalog Number:
    10-1311
    Activity:
    NEDD8 activating enzyme inhibitor
    Chemical Name:
    ((1S,2S,4R)-4-(4-(((S)-2,3-Dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate; Pevonedistat
    Molecular Weight:
    443.53
    Molecular Formula:
    C21H25N5O4S
    Solubility:
    Soluble in DMSO (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $60.00
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  • Necrosulfonamide | Necroptosis inhibitor / MLKL inhibitor

    CAS:
    1360614-48-7
    Catalog Number:
    10-4860
    Activity:
    Necroptosis inhibitor / MLKL inhibitor
    Chemical Name:
    (2E)-N-[4-[[(3-Methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide
    Molecular Weight:
    461.47
    Molecular Formula:
    C18H15N5O6S2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Yellow solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
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  • Nigericin Na | Induces rapid intracellular acidification

    CAS:
    28643-80-3
    Catalog Number:
    10-2089
    Activity:
    Induces rapid intracellular acidification
    Alternate Names:
    Antibiotic K178, Antibiotic X-464, Azalomycin M, PolyetherinA
    Molecular Weight:
    746.96
    Molecular Formula:
    C40H57O11 Na
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $50.00
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  • Nilotinib | BCR-ABL inhibitor

    CAS:
    641571-10-0
    Catalog Number:
    10-2152
    Activity:
    BCR-ABL inhibitor
    Chemical Name:
    4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
    Alternate Names:
    AMN107
    Molecular Weight:
    529.52
    Molecular Formula:
    C28H22F3N7O
    Solubility:
    Soluble in DMSO (up to 50 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $30.00
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  • Nocodazole | Microtubule inhibitor

    CAS:
    31430-18-9
    Catalog Number:
    10-2387
    Activity:
    Microtubule inhibitor
    Alternate Names:
    R-17934
    Chemical Name:
    Methyl[5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate
    Molecular Weight:
    301.32
    Molecular Formula:
    C14H11N3O3S
    Solubility:
    Soluble in DMSO (up to 10 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT (des.)
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
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