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  • GSK2879552 | Potent and selective LSD1 inhibitor

    CAS:
    1401966-69-5
    Catalog Number:
    10-4020
    Activity:
    Potent and selective LSD1 inhibitor
    Chemical Name:
    4-[[4-[[[(1R,2S)-2-Phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]benzoic acid dihydrochloride
    Molecular Weight:
    437.40
    Molecular Formula:
    C23H28N2O2 • HCl
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Water (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $80.00
  • GSK2982772 | RIP1 inhibitor

    CAS:
    1622848-92-3
    Catalog Number:
    10-4792
    Activity:
    RIP1 kinase inhibitor
    Chemical Names:
    (S)-5-Benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b]-[1,4]oxazepin-3-yl)-4H-1,2,4-traizole-3-carboxamide; GSK772
    Molecular Weight:
    377.40
    Molecular Formula:
    C20H19N5O3
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $95.00
  • GSK3326595 | Selective PRMT5 inhibitor

    CAS:
    1616392-22-3
    Catalog Number:
    10-4028
    Activity:
    Selective PRMT5 inhibitor
    Chemical Name:
    6-[(1-Acetylpiperidine-4-yl)amino]-N-[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropyl]pyrimidine-4-carboxamide
    Alternate Name:
    EPZ015938
    Molecular Weight:
    452.56
    Molecular Formula:
    C24H32N6O3
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $50.00
  • GSK4112 | Rev-Erbα agonist

    CAS:
    1216744-19-2
    Catalog Number:
    10-5493
    Activity:
    Rev-Erbα agonist
    Chemical Names:
    N-[(4-Chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl]glycine, 1,1-dimethyl ester
    Alternate Name:
    SR6452
    Molecular Weight:
    396.89
    Molecular Formula:
    C18H21ClN2O4S
    Solubility:
    Soluble in DMSO (50 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $55.00
  • GSK417651A | TRPC3/6 blocker

    CAS:
    736945-96-3
    Catalog Number:
    10-1434
    Activity:
    TRPC3/6 blocker
    Chemical Name:
    (3,4-Dihydroisoquinolin-2(1H)-yl)(2-((4-methoxyphenyl)amino)thiazol-4-yl)methanone
    Molecular Weight:
    365.46
    Molecular Formula:
    C20H19N3O2S
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
    Physical Properties:
    Yellow solid
    Purity:
    99% by HPLC
    NMR (Conforms)
    Storage Temperature:
    RT (des.)
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $100.00
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