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Product Details

TPEN | Intracellular Zn2+ chelator

TPEN (16858-02-9) is a cell permeable metal chelator. Frequently used to study effects of zinc depletion on cellular processes.1,2

References/Citations
1) Chimienti et al. (2001) Role of cellular zinc in programmed cell death: temporal relationship between zinc depletion, activation of caspases and cleavage of Sp family transcription factors; Biochem. Pharmacol. 62 51
2) Meplan et al. (2000) Metalloregulation of the tumor suppressor protein p53: zinc mediates the renaturation of p53 after exposure to metal chelators in vitro and in intact cells; Oncogene 19 5227

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TPEN | 168858-02-9 | Structure | Supplier

Catalog#  10-1228

$86.00
Quantity
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee.
 
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CAS:
16858-02-9
Catalog Number:
10-1228
Activity:
Intracellular Zn2+ chelator
Chemical Name:
N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine
Molecular Weight:
424.54
Molecular Formula:
C26H28N6
Solubility:
Soluble in DMSO (up to 10 mg/ml).
Physical Properties:
Off-white or tan solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C (des.)
Stability:
Stable for 2 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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