Veratramine (60-70-8) is a teratogenic steroidal alkaloid found in the corn lily (Veratrum sp.).1,2 It is an analog of cyclopamine which can inhibit the hedgehog signaling pathway-dependent proliferation in NIH/3T3 cells at 8 μM.1 Cell permeable.
SPECIAL HANDLING PRECAUTIONS: This product is teratogenic. Women who are, or may be pregnant should not handle veratramine
1) Tang et al. (2010), Antitumor and antiplatelet activity of alkaloids from veratrum dahuricum; Phytother. Res., 24 821
2) Mahindroo et al. (2009), Hedgehog-Gli signaling pathway inhibitors as anticancer agents; J. Med. Chem., 52 3829