Autophagy

  • 3-Methyladenine | Autophagosome inhibitor

    CAS:
    5142-23-4
    Catalog Number:
    10-2686
    Activity:
    Autophagosome inhibitor
    Alternate Names:
    3-MA
    Chemical Name:
    3-Methyl-3H-purin-6-amine
    Molecular Weight:
    149.15
    Molecular Formula:
    C6H7N5
    Solubility:
    Soluble in DMSO (up to 3 mg/ml), or in DMF (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $30.00
  • AICAR | AMPK activator

    CAS:
    2627-69-2
    Catalog Number:
    10-1092
    Activity:
    AMPK activator
    Alternate Names:
    Acadesine
    Chemical Name:
    5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside
    Molecular Weight:
    258.24
    Molecular Formula:
    CH14N4O5
    Solubility:
    Soluble in DMSO (up to 15 mg/ml) or in Water (up to 15 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    >99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date  of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
  • AR7 | Activates chaperone mediated autophagy

    CAS:
    80306-38-3
    Catalog Number:
    10-5515
    Activity:
    Activates chaperone mediated autophagy
    Chemical Names:
    7-Chloro-3-(4-methylphenyl)-2H-1,4-benzoxazine
    Molecular Weight:
    257.72
    Molecular Formula:
    C15H12ClNO
    Solubility:
    Soluble in DMSO (30 mg/ml)
    Physical Properties:
    Pale pink solid
    Purity:
    >98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $70.00
  • C2-Dihydroceramide | Autophagy inducer

    CAS:
    13031-64-6
    Catalog Number:
    10-1381
    Activity:
    Autophagy inducer
    Chemical Name:
    N-Acetyl-D-erythro-sphinganine
    Molecular Weight:
    343.54
    Molecular Formula:
    C20H41NO3
    Solubility:
    Soluble in DMSO (up to 5 mg/ml, with warming).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 week.
    Shipping Code:
    RT
    From $60.00
  • Chloroquine phosphate | Antimalarial/Autophagy inhibitor

    CAS:
    50-63-5
    Catalog Number:
    10-2473
    Activity:
    Antimalarial/Autophagy inhibitor
    Chemical Names:
    N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine, diphosphate
    Molecular Weight:
    515.87
    Molecular Formula:
    C18H26ClN3·2H3PO4
    Solubility:
    Soluble in Water (25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $25.00
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