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Autophagy

  • Spautin-1 | Inhibits autophagy by inhibiting USP 10 and 13

    CAS:
    1262888-28-7
    Catalog Number:
    10-1367
    Activity:
    Inhibits autophagy by inhibiting USP 10 and 13
    Chemical Name:
    6-Fluoro-N[(4-fluorophenyl)methyl]-4-quinazolinamine
    Molecular Weight:
    271.27
    Molecular Formula:
    C15H11F2N3
    Solubility:
    Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 15 mg/ml with warming).
    Physical Properties:
    Tan solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $65.00
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  • STF-62247 | Autophagy inducer

    CAS:
    315702-99-9
    Catalog Number:
    10-1375
    Activity:
    Autophagy inducer
    Chemical Name:
    N-(3-Methylphenyl)-4-(4-pyridinyl)-2-thiazolamine
    Molecular Weight:
    477.41
    Molecular Formula:
    C15H13N3S
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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  • Temozolomide | Autophagy inducer

    CAS:
    85622-93-1
    Catalog Number:
    10-2390
    Activity:
    Autophagy inducer
    Alternate Names:
    NSC-362856
    Chemical Name:
    8-Carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one
    Molecular Weight:
    194.15
    Molecular Formula:
    C6H6N6O2
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $75.00
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  • Thapsigargin | SERCA inhibitor

    CAS:
    67526-95-8
    Catalog Number:
    10-2105
    Activity:
    SERCA inhibitor
    Chemical Name:
    Isolated from Thapsia garganica
    Molecular Weight:
    650.77
    Molecular Formula:
    C34H50O12
    Solubility:
    Soluble in DMSO (up to 65 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    Colorless waxy solid / film
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
    Shipping Code:
    RT
    From $60.00
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  • Torin1 | mTOR inhibitor

    CAS:
    1222998-36-8
    Catalog Number:
    10-3013
    Activity:
    mTOR inhibitor
    Chemical Name:
    1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-benzo[h]-1,6-naphthyridin-2(1H)-one
    Molecular Weight:
    607.62
    Molecular Formula:
    C35H28F3N5O2
    Solubility:
    Soluble in DMSO (up to 8 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $70.00
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Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

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