Antifungals
Antifungals are used in tissue culture and medicine to prevent or slow growth of fungus and yeast. These drugs have a variety of mechanisms of action, including disruption of fungal cell wall and membrane structure, as well as inhibition of essential biochemical pathways such as mitosis or pyrimidine synthesis.
-
Griseofulvin | Inhibitor of centrosomal clustering
From $40.00CAS:126-07-8Catalog Number:10-2745Activity:Inhibitor of centrosomal clusteringChemical Name:Fermentation product from Penicili>ium sp.Molecular Weight:352.77Molecular Formula:C17H17ClO6Solubility:Soluble in DMSO (up to 40 mg/ml), in DMF (up to 50 mg/ml), or in Ethanol (up to 5 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol, or DMF may be stored at -20° for up to 3 months.Shipping Code:RT -
Ilicicolin H | Cytochrome bc1 reductase inhibitor
From $130.00CAS:12689-26-8Catalog Number:10-3243Activity:Cytochrome bc1 reductase inhibitorMolecular Weight:433.54Molecular Formula:C27H31NO4Solubility:Soluble in DMSOPhysical Properties:Yellow amorphous solidPurity:95% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Itraconazole | Autophagy inducer / Inhibits glioblastoma growth
From $45.00CAS:84625-61-6Catalog Number:10-2033Activity:Autophagy inducer / Inhibits glioblastoma growthAlternate Names:Oriconazole; R51211Molecular Weight:705.63Molecular Formula:C35H36Cl2N8O4Solubility:Soluble in DMSO (up to 1.5 mg/ml with warming)Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT -
Ketoconazole | Cytochrome P450 Inhibitor
From $45.00CAS:65277-42-1Catalog Number:10-1015Activity:Cytochrome P450 inhibitorChemical Name:(±)-1-[4-(4-{[-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethan-1-oneMolecular Weight:531.43Molecular Formula:C26H28Cl2N4O4Solubility:Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).Physical Properties:Off-white solidPurity:>98% by TLCStorage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
Pimaricin (Natamycin) | Antifungal Polyene macrolide
From $48.00CAS:7681-93-8Catalog Number:10-2742Activity:Antifungal Polyene macrolideAlternate Names:NatamycinChemical Name:Fermentation product from Streptomyces chattanoogensisMolecular Weight:665.74Molecular Formula:C3347NO13Solubility:Soluble in DMSO (up to 7 mg/ml). Only slightly soluble in Ethanol (less than 1 mg/ml).Physical Properties:Cream colored solidPurity:95% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.Shipping Code:RT -
Sulconazole | Antifungal/ Prevents cancer stem cell formation
From $55.00CAS:61318-91-0Catalog Number:10-3955Activity:Antifungal/Prevents cancer stem cell formationChemical Names:1-[2-[(4-Chlorophenyl)methylsulfanyl]-2-(2,4-dichlorophenyl)ethyl]imidazole nitrateMolecular Weight:460.75Molecular Formula:C18H15Cl3N2S·HNO3Solubility:Soluble in DMSO (up to 25 mg/ml)Physical Properties:White solidPurity:>98% TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT
