ATPase
ATPases are mainly transmembrane enzymes found in eukaryotic (mitochondrial, chloroplast, plasma or vacuolar membranes) and prokaryotic (plasma membrane) cells. They catalyze the breakdown of ATP into ADP, generating an electrical potential that is harnessed for energy to perform cellular functions. Because of this, they are critical for fundamental cellular processes such as DNA replication and repair, protein synthesis, cell proliferation, pH homeostasis, and intracellular transport. Small molecule ATPase inhibitors have been used to treat infectious diseases, gastrointestinal reflux, and cancer.
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Bafilomycin A1 | Vacuolar H+ ATPase inhibitor
From $40.00CAS:88899-55-2Catalog Number:10-2060Activity:Vascular H+-ATPase inhibitorMolecular Weight:622.84Molecular Formula:C35H58O9Solubility:Soluble in DMSO (up to 5 mg/ml, with warming).Physical Properties:Off-white or yellow filmPurity:95% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
CDN1163 | SERCA activator
From $55.00CAS:892711-75-0Catalog Number:10-4627Activity:Allosteric SERCA activatorChemical Names:4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamideMolecular Weight:320.39Molecular Formula:C20H20N2O2Solubility:Soluble in DMSO (>25 mg/ml)Physical Properties:White solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Concanamycin A | V-ATPase inhibitor
From $60.00CAS:80890-47-7Catalog Number:10-2905Activity:V-ATPase inhibitorAlternate Name:FolimycinMolecular Weight:866.09Molecular Formula:C46H75NO14Solubility:Soluble in DMSOPhysical Properties:White solid or lyophilized solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
DBeQ | p97 inhibitor
From $65.00CAS:177355-84-9Catalog Number:10-1196Activity:p97 inhibitorChemical Name:N,N’-Dibenzylquinazoline-2,4-diamineMolecular Weight:340.43Molecular Formula:C22H20N4Solubility:Soluble in DMSO (up to 25 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.Shipping Code:RT
