ATPase
ATPases are mainly transmembrane enzymes found in eukaryotic (mitochondrial, chloroplast, plasma or vacuolar membranes) and prokaryotic (plasma membrane) cells. They catalyze the breakdown of ATP into ADP, generating an electrical potential that is harnessed for energy to perform cellular functions. Because of this, they are critical for fundamental cellular processes such as DNA replication and repair, protein synthesis, cell proliferation, pH homeostasis, and intracellular transport. Small molecule ATPase inhibitors have been used to treat infectious diseases, gastrointestinal reflux, and cancer.
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Dihydroouabain | Endogenous ouabain-like factor
From $75.00CAS:1183-35-3Catalog Number:10-3125Activity:Endogenous ouabain-like factorChemical Names:3-[(6-Deoxyhexopyranosyl)oxy]-1,5,11,14,19-pentahydroxycardanolideMolecular Weight:586.68Molecular Formula:C29H46O12Solubility:Soluble in DMSO (30 mg/ml); Ethanol (30 mg/ml)Physical Properties:White solidPurity:>95% HPLC/TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT -
MDBN | p97 inhibitor
From $40.00CAS:1485-00-3Catalog Number:10-1318Activity:p97 inhibitorChemical Name:3,4-Methylenedioxy-ß-nitrostyreneMolecular Weight:193.16Molecular Formula:C9H7NO4Solubility:Soluble in DMSO (up to 50 mg/ml).Physical Properties:Yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:RTStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
ML241 | p97 AAA ATPase inhibitor
From $90.00CAS:1346528-06-0Catalog Number:10-1555Activity:p97 AAA ATPase inhibitorChemical Name:N-Benzyl-2-(2,3-dihydro-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydroquinazolin-4-amineAlternate Name:CID49830260Molecular Weight:372.46Molecular Formula:C23H24N4OSolubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 14 mg/ml with warming).Physical Properties:Pale yellow solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
Nigericin Na | Induces rapid intracellular acidification
From $50.00CAS:28643-80-3Catalog Number:10-2089Activity:Induces rapid intracellular acidificationAlternate Names:Antibiotic K178, Antibiotic X-464, Azalomycin M, PolyetherinAMolecular Weight:746.96Molecular Formula:C40H57O11 NaSolubility:Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 20 mg/ml).Physical Properties:White solidPurity:98% by TLCStorage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.Shipping Code:RT -
Oligomycin A | Mitochondrial ATPase inhibitor
From $54.00CAS:579-13-5Catalog Number:10-5368Activity:Mitochondrial ATPase inhibitorSource:Streptomyces sp.Molecular Weight:791.06Molecular Formula:C45H74O11Solubility:Soluble in DMSO (up to 300 mg/ml); Ethanol (up to 200 mg/ml)Physical Properties:White solidPurity:>98% TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Oligomycin Complex | Mitochondrial ATPase inhibitor
From $64.00CAS:1404-19-9Catalog Number:10-2092Activity:Mitochondrial ATPase inhibitorSource:From Streptomyces sp.Molecular Weight:791.06Molecular Formula:C45H74O11 (for Oligomycin A)Solubility:Soluble in DMSO (up to 300 mg/ml) or in Ethanol (up to 200 mg/ml)Physical Properties:White solidPurity:Mixture of Oligomycin A (67.5%), B (19.4%), and C (9.8%)
97% by TLC
NMR: (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.Shipping Code:RT
