ATPase
ATPases are mainly transmembrane enzymes found in eukaryotic (mitochondrial, chloroplast, plasma or vacuolar membranes) and prokaryotic (plasma membrane) cells. They catalyze the breakdown of ATP into ADP, generating an electrical potential that is harnessed for energy to perform cellular functions. Because of this, they are critical for fundamental cellular processes such as DNA replication and repair, protein synthesis, cell proliferation, pH homeostasis, and intracellular transport. Small molecule ATPase inhibitors have been used to treat infectious diseases, gastrointestinal reflux, and cancer.
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Ouabain | Na+/K+ ATPase inhibitor
From $30.00CAS:11018-89-6Catalog Number:10-1248Activity:Na+/K+ ATPase inhibitorChemical Name:3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11_,14,19-pentahydoxycard-20(22)-enolide octahydrateMolecular Weight:728.79Molecular Formula:C29H44O12·8(H2O)Solubility:Soluble in DMSO (up to 50 mg/ml), or in Water (up to 10 mg/ml).Physical Properties:White solidPurity:99% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Protect from exposure to moisture. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.Shipping Code:RT -
Rbin-1 | Eukaryotic ribosome assembly inhibitor
From $50.00CAS:328023-11-6Catalog Number:10-4606Activity:Eukaryotic ribosome assembly inhibitorChemical Name:3-[(2-Methyl-2-propen-1-yl)sulfanyl]-5H-[1,2,4]triazino[5,6-b]indoleMolecular Weight:256.33Molecular Formula:C13H12N4SSolubility:Soluble in DMSO (up to at least 25 mg/ml)Physical Properties:Pale yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Thapsigargin | SERCA inhibitor
From $60.00CAS:67526-95-8Catalog Number:10-2105Activity:SERCA inhibitorChemical Name:Isolated from Thapsia garganicaMolecular Weight:650.77Molecular Formula:C34H50O12Solubility:Soluble in DMSO (up to 65 mg/ml) or in Ethanol (up to 20 mg/ml).Physical Properties:Colorless waxy solid / filmPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.Shipping Code:RT -
Xanthohumol | VCP inhibitor / Autophagy inhibitor
From $75.00CAS:6754-58-1Catalog Number:10-1188Activity:VCP inhibitor / Autophagy inhibitorMolecular Weight:354.41Molecular Formula:C21H22O5Solubility:Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 35 mg/ml).Physical Properties:Yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.Shipping Code:RT
