ATPase

ATPases are mainly transmembrane enzymes found in eukaryotic (mitochondrial, chloroplast, plasma or vacuolar membranes) and prokaryotic (plasma membrane) cells. They catalyze the breakdown of ATP into ADP, generating an electrical potential that is harnessed for energy to perform cellular functions. Because of this, they are critical for fundamental cellular processes such as DNA replication and repair, protein synthesis, cell proliferation, pH homeostasis, and intracellular transport. Small molecule ATPase inhibitors have been used to treat infectious diseases, gastrointestinal reflux, and cancer.

  • Omeprazole | Proton pump inhibitor / Antiviral

    CAS:
    73590-58-6
    Catalog Number:
    10-2822
    Activity:
    Proton pump inhibitor / Antiviral
    Chemical Name:
    5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
    Molecular Weight:
    345.42
    Molecular Formula:
    C17H19N3O3S
    Solubility:
    Soluble in DMSO (up to 35 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 months.
    Shipping Code:
    RT
    From $38.00
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  • Ouabain | Na+/K+ ATPase inhibitor

    CAS:
    11018-89-6
    Catalog Number:
    10-1248
    Activity:
    Na+/K+ ATPase inhibitor
    Chemical Name:
    3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11_,14,19-pentahydoxycard-20(22)-enolide octahydrate
    Molecular Weight:
    728.79
    Molecular Formula:
    C29H44O12·8(H2O)
    Solubility:
    Soluble in DMSO (up to 50 mg/ml), or in Water (up to 10 mg/ml).
    Physical Properties:
    White solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Protect from exposure to moisture. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $30.00
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  • Rbin-1 | Eukaryotic ribosome assembly inhibitor

    CAS:
    328023-11-6
    Catalog Number:
    10-4606
    Activity:
    Eukaryotic ribosome assembly inhibitor
    Chemical Name:
    3-[(2-Methyl-2-propen-1-yl)sulfanyl]-5H-[1,2,4]triazino[5,6-b]indole
    Molecular Weight:
    256.33
    Molecular Formula:
    C13H12N4S
    Solubility:
    Soluble in DMSO (up to at least 25 mg/ml)
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $50.00
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  • Spastazoline | Spastin inhibitor

    CAS:
    2351882-11-4
    Catalog Number:
    10-4240
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  • Thapsigargin | SERCA inhibitor

    CAS:
    67526-95-8
    Catalog Number:
    10-2105
    Activity:
    SERCA inhibitor
    Chemical Name:
    Isolated from Thapsia garganica
    Molecular Weight:
    650.77
    Molecular Formula:
    C34H50O12
    Solubility:
    Soluble in DMSO (up to 65 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    Colorless waxy solid / film
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
    Shipping Code:
    RT
    From $60.00
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  • Xanthohumol | VCP inhibitor / Autophagy inhibitor

    CAS:
    6754-58-1
    Catalog Number:
    10-1188
    Activity:
    VCP inhibitor / Autophagy inhibitor
    Molecular Weight:
    354.41
    Molecular Formula:
    C21H22O5
    Solubility:
    Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 35 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $75.00
    View Product This product has multiple variants. The options may be chosen on the product page
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