Cycloastragenol | Telomerase activator/Senolytic agent
Cycloastragenol (84605-18-5) is a novel naturally occurring terpenoid found in Astragalus which was shown to be a telomerase activator. In CD8+ T lymphocytes from HIV-infected donors
Complex Carbohydrates
Migalastat HCl | Galactosidase inhibitor/Pharmacological chaperone
Migalastat (75172-81-5) is a potent, selective, and orally available inhibitor of α-galactosidase A (IC50= 40 nM).1 It binds to mutant misfolded α-GalA shifting the folding behavior
ML401 | EBI2 (GPR183) antagonist
ML401 (1597489-14-9) is a potent antagonist of GPR183 (IC50 = 1.03 nM), also known as EBI2 or Epstein-Barr virus-induced gene 2. ML401 inhibited 7α,25-dihydroxycholesterol-induced RS11846 cell
Cafestol | Neuroprotective
Cafestol (469-83-0) is a bioactive diterpene found in coffee.1 It displays a number of interesting protective effects including stimulation of glutathione S-transferase activity1, and protection against
icFSP1 | Ferroptosis suppressor protein (FSP1) inhibitor
Ferroptosis suppressor protein-1 (FSP1) along with ubiquinone and NAD(P)H/H+ has been identified as a second ferroptosis suppressing system which prevents lipid peroxidation independently of the cysteine-glutathione-glutathione
