Indisulam | RBM39 Molecular glue
Indisulam (165668-41-7) was originally described as a potent antitumor agent that targeted the G1 phase of cell cycle via suppression of activation of CDK2 and cyclin
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Indisulam (165668-41-7) was originally described as a potent antitumor agent that targeted the G1 phase of cell cycle via suppression of activation of CDK2 and cyclin
TRIM-473 is a ligand (EC50 = 5.3 µM) for the PRY-SPRY domain of the RING ligase TRIM58. An interesting new tool for the development of heterobifunctional
GSK2636771 (1372540-25-4) is a potent, selective (>1000-fold over α, 10-fold over δ, and >2000-fold over γ), and orally bioavailable inhibitor of PI3Kß (IC50 = 5.2 nM).1
LDC1267 (1361030-48-9) is a potent and selective inhibitor of the TAM kinases Tyro3, Axl, and Mer (IC50s respectively: 8 nM, <5 nM, 29 nM).1 It was
XMU-MP-1 (2061980-01-4) is a potent, reversible, and selective inhibitor of the HIPPO pathway kinases MST1 and MST2 (IC50s = 71 nM and 38 nM respectively).1 It
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