Hedgehog Pathway

  • Itraconazole | Autophagy inducer / Inhibits glioblastoma growth

    CAS:
    84625-61-6
    Catalog Number:
    10-2033
    Activity:
    Autophagy inducer / Inhibits glioblastoma growth
    Alternate Names:
    Oriconazole; R51211
    Molecular Weight:
    705.63
    Molecular Formula:
    C35H36Cl2N8O4
    Solubility:
    Soluble in DMSO (up to 1.5 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
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  • Jervine | Hedgehog pathway inhibitor

    CAS:
    469-59-0
    Catalog Number:
    10-2388
    Activity:
    Hedgehog pathway
    Alternate Names:
    11-Ketocyclopamine
    Chemical Name:
    (3β,23β)-17,23-Epoxy-3-hydroxyveratraman-11-one
    Molecular Weight:
    425.62
    Molecular Formula:
    C27H39NO3
    Solubility:
    Soluble in DMSO (up to 5 mg/ml), in DMF (up to 6 mg/ml), or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO, ethanol or DMF may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $85.00
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  • Purmorphamine | Smoothened activator

    CAS:
    483367-10-8
    Catalog Number:
    10-4622
    Activity:
    Smoothened activator
    Chemical Name:
    1-(1-Naphthoxy)-6-(4-morpholinoanilino)-9-cyclohexylpurine
    Molecular Weight:
    520.62
    Molecular Formula:
    C31H32N6O2
    Solubility:
    Soluble in DMSO (up to 10 mg/ml)
    Physical Properties:
    Off-white solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
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  • SAG | Smoothened agonist

    CAS:
    364590-63-6
    Catalog Number:
    10-4525
    Activity:
    Smoothened agonist
    Alternate Names:
    Smoothened Agonist
    Chemical Name:
    3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiiophene-2-carboxamide dihydrochloride
    Molecular Weight:
    562.98
    Molecular Formula:
    C28H28ClN3OS 2HCl
    Solubility:
    Soluble in DMSO (up to 20 mg/ml), in DMF (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    Solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Shipping Code:
    RT
    From $35.00
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  • Salinomycin Na | Cancer stem cell inhibitor

    CAS:
    55721-31-8
    Catalog Number:
    10-2654
    Activity:
    Cancer stem cell inhibitor
    Chemical Name:
    from Streptomyces albus
    Molecular Weight:
    772.98
    Molecular Formula:
    C42H69O11 Na
    Solubility:
    Soluble in DMSO.
    Physical Properties:
    White solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • Synaptamide | Endogenous agonist at GPR110

    CAS:
    162758-94-3
    Catalog Number:
    10-1194
    Activity:
    Endogenous agonist at GPR110
    Chemical Name:
    N-Docosahexaenoylethanolamide
    Alternate Names:
    DHA-ethanolamide
    Molecular Weight:
    371.56
    Molecular Formula:
    C24H37NO2
    Solubility:
    Soluble in DMSO (up to 35 mg/ml)
    Physical Properties:
    Colorless to yellow oil
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -80°C, protect from exposure to air.
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored under inert gas at -80°C for up to 3 months.
    Shipping Code:
    Dry Ice
    From $35.00
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