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Product Details

Brefeldin A | Inhibits intracellular transport

Brefeldin A (20350-15-6) is a specific inhibitor of protein translocation from endoplasmic reticulum to Golgi. Induces apoptosis. Brefeldin A activates sphingomyelin metabolism. Cell permeable.

References/Citations
1) Fujiwara et al. (1988) Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum,; J. Biol. Chem., 263 18545
2) Shao et al. (1996), Brefeldin A is a potent inducer of apoptosis in human cancer cells independently of p53; Exp. Cell Res., 227 190
3) Linardic et al. (1996), Brefeldin A promotes hydrolysis of sphingomyelin; Cell Growth Differ., 7 765

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Brefeldin A | 20350-15-6 | Structure | Supplier

Catalog#  10-1071

$30.00
Quantity
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CAS:
20350-15-6
Catalog Number:
10-1071
Activity:
Inhibits intracellular transport
Alternate Names:
Fermentation product from Penicillium brefeldianum
Molecular Weight:
280.37
Molecular Formula:
C16H24O4
Solubility:
Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 25 mg/ml).
Physical Properties:
White solid
Purity:
99% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Shipping Code:
RT
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications.

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