Programmed cell death
Showing 1–12 of 128 results
-
New Products
(+)-Cedrol | Anticancer natural product
Cedrol is a sesquiterpene alcohol found in conifers mainly of the genera Cupressus, Juniperus, and Cedrus. It has been found to possess significant...$30.00 – $80.00 Select options -
Cancer
10058-F4 | Myc inhibitor
10058-F4 (403811-55-2) effectively disables c-Myc by inhibiting the c-Myc-Max association and function.1 It prevents the growth of fibroblasts in a...$54.00 – $200.00 Select options -
Angiogenesis
17-DMAG | HSP90 inhibitor
17-DMAG (150270-08-9) is an analog of geldanamycin (Cat.# 10-1084) that displays superior pharmacological properties. 17-DMAG inhibits HSP90 and in...$32.00 – $80.00 Select options -
Apoptosis
5-Fluorouridine | Proapoptotic antiproliferative agent
5-Fluorouridine (316-46-1) is an inhibitor of ribozyme self-cleavage in mammalian cells.1 Induces apoptosis in HCT-116 colorectal carcinoma cells ...$60.00 – $130.00 Select options -
Apoptosis
ABT-263 | Bcl-2 family inhibitor; Senolytic agent
ABT-263 (923564-51-6) is a potent and selective Bcl-2 family inhibitor / BH3 domain mimetic which binds to Bcl-2, Bcl-xL and Bcl-w (Ki<1 nM). A ...$60.00 – $200.00 Select options -
New Products
ABT-737 | Senolytic Bcl2 inhibitor
ABT-737 (852808-04-9) is an inhibitor of anti-apoptotic proteins from the Bcl family: Bcl-2, Bcl-X(L), and Bcl-w (Ki < 1 nM) that causes regress...$80.00 – $245.00 Select options -
Apoptosis
Adapalene | Retinoid RARbeta, gamma agonist
Adapalene (106685-40-9) is a stable analog of retinoic acid that acts as a selective agonist for RARβ and RARγ. Adapalene also inhibits proliferati...$30.00 – $50.00 Select options -
Apoptosis
AG-1296 | PDGFR kinase inhibitor
AG-1296 (146535-11-7) is a potent inhibitor of PDGF receptor kinase (IC50 = 1 μM), c-kit and FGF kinase. Induces apoptosis in H526, small-cell lung...$60.00 – $260.00 Select options -
New Products
Altretamine | Ferroptosis inducer
Altretamine (645-05-6) induces ferroptosis by inhibiting glutathione peroxidase 4 (GPX4) which causes accumulation of lipid hydroperoxides.1 Ferrop...$35.00 – $100.00 Select options -
Apoptosis
Ansamitocin P3 | Microtubule depolymerizer
Ansamitocin P3 (66547-09-9) is a fungal metabolite from Actinosynnema pretiosum which binds to the phomopsin A/rhizoxin site on tubulin.1,2 Ansamit...$50.00 – $120.00 Select options -
Apoptosis
Aphidicolin | DNA polymerase inhibitor
Aphidicolin (38966-21-1) specifically inhibits DNA polymerase α and δ via binding to the enzyme, in eukaryotic cells such as the HeLa cell line, wi...$76.00 – $280.00 Select options -
Antifungals
Apicidin | HDAC inhibitor
Apicidin (183506-66-3) is a fungal toxin that is a potent, cell permeable inhibitor of histone deacetylases (HDAC's).1 It also displays antitumor p...$55.00 – $220.00 Select options
