Cell Cycle
Showing 1–12 of 78 results
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CD45
(+/-) RK-682 | Tyrosine phopshatase inhibitor
RK-682 (150627-37-5) is a protein tyrosine phosphatase inhibitor (IC50's = 54 7mu;M for CD45, 2.0 μM for VHR; did not inhibit cdc25B) originally is...$75.00 – $295.00 Select options -
Cardiovascular
1-EBIO | K+ channel activator; Promotes cardiomyocyte differentiation
1-EBIO (10045-45-1) is a direct activator of small-conductance Ca2+-activated K+ channels (SK) which dose-dependently relaxes rat mesenteric vessel...$40.00 – $148.00 Select options -
Cancer
10058-F4 | Myc inhibitor
10058-F4 (403811-55-2) effectively disables c-Myc by inhibiting the c-Myc-Max association and function1. It prevents the growth of fibroblasts in a...$50.00 – $200.00 Select options -
Approved Drugs
Abemaciclib | Potent and selective CDK 4/6 inhibitor
Abemaciclib (1231930-82-7) is a potent and selective CDK4/6 inhibitor (IC50 = 2 nM and 10 nM respectively).1 It caused G1 cell cycle arrest in colo...$50.00 – $115.00 Select options -
Aurora kinase
Alisertib | Potent and selective inhibitor of Aurora A / Destabilizes Myc
Alisertib (MLN8237, 1028486-01-2) is a highly selective and potent (IC50 = 1 nM) cell permeable inhibitor of Aurora A with off-target binding at GA...$60.00 – $230.00 Select options -
Calpains
ALLN | Calpain inhibitor
ALLN (110044-82-1) is a cell-permeable, peptide aldehyde inhibitor of calpain I (Ki=190 nM), calpain II (Ki=150 nM), cathepsin L (Ki=0.5 nM) and ot...$50.00 – $188.00 Select options -
Angiogenesis
Alsterpaullone Supplier | CAS 237430-03-4 | Focus Biomolecules
Alsterpaullone (237430-03-4) is a potent and selective inhibitor of GSK-3β and CDK5/p25. Potent inhibitor of CDK1/cyclin B (IC50 = 35 nM)1. Alsterp...$56.00 – $224.00 Select options -
Apoptosis
Aphidicolin | DNA polymerase inhibitor
Aphidicolin (38966-21-1) specifically inhibits DNA polymerase α and δ via binding to the enzyme, in eukaryotic cells such as the HeLa cell line, wi...$70.00 – $280.00 Select options -
Antifungals
Apicidin | HDAC inhibitor
Apicidin (183506-66-3) is a fungal toxin that is a potent, cell permeable inhibitor of histone deacetylases (HDAC's).1 It also displays antitumor p...$55.00 – $220.00 Select options -
Angiogenesis
Apigenin | Protein kinase inhibitor
Apigenin (520-36-5) is a plant flavonoid with antioxidant properties. It has been reported to have myriad effects on biochemical pathways including...$36.00 – $130.00 Select options -
New Products
AZ3146 | Mps1 kinase inhibitor
AZ3146 (1124329-14-1) is a potent (IC50 = 35 nM) and selective monopolar spindle 1 (Mps1/TTK) kinase inhibitor.1 Mps1 has an essential role in the ...$60.00 – $195.00 Select options -
New Products
AZD1152-HQPA | Aurora B kinase inhibitor
AZD1152-HQPA (722544-51-6) is a potent and highly selective inhibitor of Aurora B.1 Aurora B Ki = 0.36 nM; Aurora A Ki = 1,369 nM.2 It inhibits the...$50.00 – $150.00 Select options
