CANCER
Immunology
Stem Cells
Cell Death
Neurodegeneration
Cellular Stress
Inflammation
Proteasome
Diabetes
View All Physiological Processes & Diseases
Cell death can be divided in two major categories. Necrosis results from cellular injury caused by external factors such as trauma or infection. Programmed cell death is a regulated process that is mediated by various intracellular programs. Types of programmed cell death include apoptosis, anoikis, necroptosis, ferroptosis, pyroptosis, and parthanatos. These types of programmed cell death other than apoptosis have also been termed stress-induced cell death (SCID).
Apoptosis
Z-VAD-FMK
Cell permeable, irreversible, pan-caspase inhibitor
Staurosporine
Staurosporine is a pan-kinase inhibitor widely used to induce apoptosis
C2-Ceramide
Cell permeable ceramide analog that induces apoptosis in a wide variety of cell types
Obatoclax
Obatoclax is a pan-inhibitor of Bcl-2-family proteins
Ferroptosis
Erastin
Induces ferroptosis via inhibition of the cystine-glutamate antiporter, system Xc-
Ferrostatin-1
Ferrostatin-1 is a potent inhibitor of ferroptosis
Necroptosis
7-Cl-O-Nec1
Selective inhibitor of RIP1
GSK872
GSK872 is a potent and selective inhibitor of RIP3 that blocks necroptosis and necrosis
RIPA-56
Potent and selective inhibitor of RIP1
Necrosulfonamide
MLKL inhibitor that blocks necroptosis downstream of RIP3
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