Intelliscreen™ Cholesterol Metabolites Mini-Library
Cholesterol is the primary sterol in all eukaryotes and is the precursor to bile acids, steroid hormones, vitamin D, and other important biomolecules. Many of the intermediate products of cholesterol metabolism (oxysterols) are themselves important signaling molecules involved in stem cell fate, inflammatory and immune processes, neurodegeneration and are endogenous ligands for a wide variety of cellular receptors. The IntelliscreenTM Cholesterol Metabolites mini-library is a useful tool for exploring the biology of these important molecules or as a reference for monitoring their presence in biological samples.
In Stock
Materials provided by Focus Biomolecules are for laboratory research use only and are not intended for human or veterinary applications. Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
Please note that we do not sell to individuals and that all orders placed by non-research organizations will incur a $20 restocking/refund fee
-
20(S)-Hydroxycholesterol | Smoothened activator
From $40.00CAS:516-72-3Catalog Number:10-4540Activity:Smoothened activatorChemical Name:5-Cholesten-3β, 20α-diolMolecular Weight:402.66Molecular Formula:C27H46O2Solubility:Soluble in DMSO or in Ethanol.Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
24(S)-Hydroxycholesterol | Endogenous cholesterol metabolite
From $65.00CAS:474-73-7Catalog Number:10-1331Activity:Endogenous cholesterol metaboliteMolecular Weight:402.66Molecular Formula:C27H46O2Solubility:Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).Physical Properties:White solidPurity:99% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.Shipping Code:RT -
24(S),25-Epoxycholesterol | LXR agonist
From $105.00CAS:77058-74-3Catalog Number:10-1330Activity:LXR agonistMolecular Weight:400.65Molecular Formula:C27H44O2Solubility:Soluble in DMSO (up to 30 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.Shipping Code:RT -
25-Hydroxycholesterol | Biologically active cholesterol metabolite
From $30.00CAS:2140-46-7Catalog Number:10-4539Activity:Biologically active cholesterol metaboliteChemical Name:5-Cholesten-3β, 25-diolMolecular Weight:402.66Molecular Formula:C27H46O2Solubility:Soluble in DMSO or in Ethanol.Physical Properties:White or pale yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT -
27-Hydroxycholesterol | Cholesterol oxidation metabolite
From $40.00CAS:20380-11-4Catalog Number:10-4536Activity:Cholesterol oxidation metaboliteChemical Name:27-Hydroxycholesterol; 5,25R-Cholesten-3β,26-diolMolecular Weight:402.66Molecular Formula:C27H46O2Solubility:Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.Shipping Code:RT -
5alpha,6alpha-Epoxycholesterol | LXR ligand
From $25.00CAS:1250-95-9Catalog Number:10-4545Activity:LXR ligandChemical Name:Cholestan-5α,6α-epoxy-3β-olMolecular Weight:402.65Molecular Formula:C27H46O2Solubility:Soluble in DMSO (up to 10 mg/ml) orin Ethanol (up to 10 mg/ml).Physical Properties:White solidPurity:98% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.Shipping Code:RT -
7α-Hydroxycholesterol | Bile acid precursor
From $30.00CAS:566-26-7Catalog Number:10-4538Activity:Bile acid precursorChemical Name:5-Cholesten-3β, 7α-diolMolecular Weight:402.66Molecular Formula:C27H46O2Solubility:Soluble in DMSO or in Ethanol.Physical Properties:White or pale yellow solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.Shipping Code:RT
