Antifungals

Antifungals are used in tissue culture and medicine to prevent or slow growth of fungus and yeast. These drugs have a variety of mechanisms of action, including disruption of fungal cell wall and membrane structure, as well as inhibition of essential biochemical pathways such as mitosis or pyrimidine synthesis.

  • Amphotericin B | Antifungal agent

    CAS:
    1397-89-3
    Catalog Number:
    10-2430
    Activity:
    Antifungal agent
    Chemical Names:
    NSC 527017
    Molecular Weight:
    924.08
    Molecular Formula:
    C47H73NO17
    Solubility:
    Soluble in DMSO (18 mg/ml)
    Physical Properties:
    Yellow or orange solid
    Purity:
    90% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
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  • Beauvericin | Disrupts mitochondrial volume

    CAS:
    26048-05-5
    Catalog Number:
    10-2061
    Activity:
    Disrupts mitochondrial volume
    Chemical Names:
    Cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl]
    Molecular Weight:
    783.95
    Molecular Formula:
    C45H57N3O9
    Solubility:
    Soluble in DMSO (30 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $32.00
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  • Bithionol | Glutamate dehydrogenase inhibitor

    CAS:
    97-18-7
    Catalog Number:
    10-4567
    Activity:
    Glutamate dehydrogenase inhibitor
    Chemical Name:
    Bis(2-hydroxy-3,5-dichlorophenyl)sulfide
    Molecular Weight:
    356.05
    Molecular Formula:
    C12H6Cl4O2S
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98%
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $20.00
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  • Cercosporin | ROS-generating fungal toxin

    CAS:
    35082-49-6
    Catalog Number:
    10-3447
    Activity:
    ROS-generating fungal toxin
    Chemical Names:
    (13bR)-6,12-Dihydroxy-8,9-bis[(2R)-2-hydroxypropyl]-7,10-dimethoxy-perylo[1,12-def]-1,3-dioxepin-5,11-dione
    Alternate Name:
    NSC-153111
    Molecular Weight:
    534.52
    Molecular Formula:
    C29H26O4
    Solubility:
    Soluble in DMSO (10 mg/ml)
    Physical Properties:
    Dark red solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $60.00
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  • Cycloheximide | Protein synthesis inhibitor

    CAS:
    66-81-9
    Catalog Number:
    10-1117
    Activity:
    Protein synthesis inhibitor
    Alternate Names:
    U-4527
    Chemical Name:
    4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione
    Molecular Weight:
    281.35
    Molecular Formula:
    C15H23NO4
    Solubility:
    Soluble in Ethanol (up to 14 mg/ml) or in Water (up to 7 mg/ml).
    Physical Properties:
    White or off-white solid
    Purity:
    96% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in ethanol or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • Dehydrozingerone | Glutathione sponge

    CAS:
    1080-12-2
    Catalog Number:
    10-2526
    Activity:
    Glutathione sponge
    Chemical Name:
    (E)-4-(4-Hydroxy-3-methoxyphenyl)but-3-ene-2-one
    Molecular Weight:
    192.21
    Molecular Formula:
    C11H12O3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $35.00
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