Antifungals

Antifungals are used in tissue culture and medicine to prevent or slow growth of fungus and yeast. These drugs have a variety of mechanisms of action, including disruption of fungal cell wall and membrane structure, as well as inhibition of essential biochemical pathways such as mitosis or pyrimidine synthesis.

  • Dehydrozingerone | Glutathione sponge

    CAS:
    1080-12-2
    Catalog Number:
    10-2526
    Activity:
    Glutathione sponge
    Chemical Name:
    (E)-4-(4-Hydroxy-3-methoxyphenyl)but-3-ene-2-one
    Molecular Weight:
    192.21
    Molecular Formula:
    C11H12O3
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $35.00
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  • Griseofulvin | Inhibitor of centrosomal clustering

    CAS:
    126-07-8
    Catalog Number:
    10-2745
    Activity:
    Inhibitor of centrosomal clustering
    Chemical Name:
    Fermentation product from Penicili>ium sp.
    Molecular Weight:
    352.77
    Molecular Formula:
    C17H17ClO6
    Solubility:
    Soluble in DMSO (up to 40 mg/ml), in DMF (up to 50 mg/ml), or in Ethanol (up to 5 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO, ethanol, or DMF may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • Ilicicolin H | Cytochrome bc1 reductase inhibitor

    CAS:
    12689-26-8
    Catalog Number:
    10-3243
    Activity:
    Cytochrome bc1 reductase inhibitor
    Molecular Weight:
    433.54
    Molecular Formula:
    C27H31NO4
    Solubility:
    Soluble in DMSO
    Physical Properties:
    Yellow amorphous solid
    Purity:
    95% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $130.00
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  • Itraconazole | Autophagy inducer / Inhibits glioblastoma growth

    CAS:
    84625-61-6
    Catalog Number:
    10-2033
    Activity:
    Autophagy inducer / Inhibits glioblastoma growth
    Alternate Names:
    Oriconazole; R51211
    Molecular Weight:
    705.63
    Molecular Formula:
    C35H36Cl2N8O4
    Solubility:
    Soluble in DMSO (up to 1.5 mg/ml with warming)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
    Shipping Code:
    RT
    From $45.00
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  • Ketoconazole | Cytochrome P450 Inhibitor

    CAS:
    65277-42-1
    Catalog Number:
    10-1015
    Activity:
    Cytochrome P450 inhibitor
    Chemical Name:
    (±)-1-[4-(4-{[-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethan-1-one
    Molecular Weight:
    531.43
    Molecular Formula:
    C26H28Cl2N4O4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 20 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    >98% by TLC
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $45.00
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  • Pimaricin (Natamycin) | Antifungal Polyene macrolide

    CAS:
    7681-93-8
    Catalog Number:
    10-2742
    Activity:
    Antifungal Polyene macrolide
    Alternate Names:
    Natamycin
    Chemical Name:
    Fermentation product from Streptomyces chattanoogensis
    Molecular Weight:
    665.74
    Molecular Formula:
    C3347NO13
    Solubility:
    Soluble in DMSO (up to 7 mg/ml). Only slightly soluble in Ethanol (less than 1 mg/ml).
    Physical Properties:
    Cream colored solid
    Purity:
    95% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
    Shipping Code:
    RT
    From $48.00
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