Disease Model Inducers
In addition to exploring signaling pathways, small molecules are also used as a means to an end: to create a cell or animal model system for further research or drug screening. Focus Biomolecules offers small molecule tools to induce model systems such as: Streptozotocin (diabetes, Alzheimer’s); Kainic acid (neurodegeneration); Bleomycin sulfate (pulmonary fibrosis); and many others to create cancer or stem cell models.
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Rotenone | Mitochondrial Complex I Inhibitor
From $48.00CAS:83-79-4Catalog Number:10-2277Activity:Mitochondrial Complex I InhibitorChemical Names:(2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-oneAlternate Name:NSC-26285; NicoulineMolecular Weight:394.42Molecular Formula:C23H22O6Solubility:Soluble in DMSO (50 mg/ml)Physical Properties:Off-white solidPurity:>98% HPLC
NMR (Conforms)Storage Temperature:Room TemperatureStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.Shipping Code:RT -
Streptozotocin | Diabetes inducer
From $100.00CAS:18883-66-4Catalog Number:10-2127Activity:Diabetes inducerChemical Name:2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-D-glucoseAlternate Names:Streptozocin; U-9889Molecular Weight:265.22Molecular Formula:C8H15N3O7Solubility:Soluble in DMSO (up to 25 mg/ml) or in Water (up to 25 mg/ml)Physical Properties:Off-white solidPurity:97% by TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.Shipping Code:RT
