BiochemicalTargets

ATPase

ATPases are mainly transmembrane enzymes found in eukaryotic (mitochondrial, chloroplast, plasma or vacuolar membranes) and prokaryotic (plasma membrane) cells. They catalyze the breakdown of ATP into ADP, generating an electrical potential that is harnessed for energy to perform cellular functions. Because of this, they are critical for fundamental cellular processes such as DNA replication and repair, protein synthesis, cell proliferation, pH homeostasis, and intracellular transport. Small molecule ATPase inhibitors have been used to treat infectious diseases, gastrointestinal reflux, and cancer.

  • Bafilomycin A1 | Vacuolar H+ ATPase inhibitor

    CAS:
    88899-55-2
    Catalog Number:
    10-2060
    Activity:
    Vascular H+-ATPase inhibitor
    Molecular Weight:
    622.84
    Molecular Formula:
    C35H58O9
    Solubility:
    Soluble in DMSO (up to 5 mg/ml, with warming).
    Physical Properties:
    Off-white or yellow film
    Purity:
    95% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $40.00
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  • BRM014 | BRM/BRG1 ATPase inhibitor

    CAS:
    2270879-17-7
    Catalog Number:
    10-5244
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  • CDN1163 | SERCA activator

    CAS:
    892711-75-0
    Catalog Number:
    10-4627
    Activity:
    Allosteric SERCA activator
    Chemical Names:
    4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide
    Molecular Weight:
    320.39
    Molecular Formula:
    C20H20N2O2
    Solubility:
    Soluble in DMSO (>25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >98% HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $55.00
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  • Concanamycin A | V-ATPase inhibitor

    CAS:
    80890-47-7
    Catalog Number:
    10-2905
    Activity:
    V-ATPase inhibitor
    Alternate Name:
    Folimycin
    Molecular Weight:
    866.09
    Molecular Formula:
    C46H75NO14
    Solubility:
    Soluble in DMSO
    Physical Properties:
    White solid or lyophilized solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
    Shipping Code:
    RT
    From $60.00
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  • DBeQ | p97 inhibitor

    CAS:
    177355-84-9
    Catalog Number:
    10-1196
    Activity:
    p97 inhibitor
    Chemical Name:
    N,N’-Dibenzylquinazoline-2,4-diamine
    Molecular Weight:
    340.43
    Molecular Formula:
    C22H20N4
    Solubility:
    Soluble in DMSO (up to 25 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
    Shipping Code:
    RT
    From $65.00
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  • Dihydroouabain | Endogenous ouabain-like factor

    CAS:
    1183-35-3
    Catalog Number:
    10-3125
    Activity:
    Endogenous ouabain-like factor
    Chemical Names:
    3-[(6-Deoxyhexopyranosyl)oxy]-1,5,11,14,19-pentahydroxycardanolide
    Molecular Weight:
    586.68
    Molecular Formula:
    C29H46O12
    Solubility:
    Soluble in DMSO (30 mg/ml); Ethanol (30 mg/ml)
    Physical Properties:
    White solid
    Purity:
    >95% HPLC/TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $75.00
    View Product This product has multiple variants. The options may be chosen on the product page
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