Nuclear Import

  • Importazole | Blocks importin-ß-mediated nuclear import

    CAS:
    662163-81-7
    Catalog Number:
    10-1412
    Activity:
    Blocks importin-β-mediated nuclear import
    Alternate Names:
    IPZ
    Chemical Name:
    N-(1-Phenylethyl)-2-(pyrrolidin-1-yl)quinazolin-4-amine
    Molecular Weight:
    318.43
    Molecular Formula:
    C20H22N4
    Solubility:
    Soluble in DMSO (up to 10 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    97% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
  • Ivermectin | Nuclear transport inhibitor

    CAS:
    70288-86-7
    Catalog Number:
    10-2628
    Activity:
    Nuclear transport inhibitor
    Chemical Name:
    22,23-Dihydroavermectin B1
    Alternate Name:
    22,23-Dihydro C076B1; MK-933
    Molecular Weight:
    875.09
    Molecular Formula:
    C48H74O14 (B1a form)
    Solubility:
    Soluble in DMSO (up to 70 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    White solid
    Purity:
    98% by TLC
    NMR (Conforms)
    Contains up to 10% B1b form
    Storage Temperature:
    -20°C (des.)
    Stability:
    Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $30.00