Cell Cycle Checkpoints Archives | Focus Biomolecules

Adavosertib | Wee1 kinase inhibitor

CAS:

955365-80-7

Catalog Number:

10-4823

Activity:

Wee1 kinase inhibitor

Chemical Names:

1,2-Dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)-phenyl]amino]-2-(2-propen-1-yl)-3H-pyrazolo[3,4-d]pyrimidin-3-one

Alternate Name:

MK-1775; AZD1775

Molecular Weight:

500.61

Molecular Formula:

C₂₇H₃₂N₈O₂

Solubility:

Soluble in DMSO (70 mg/ml)

Physical Properties:

Yellow solid

Purity:

>98% HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $45.00
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AZD7762 | Checkpoint kinase 1/2 inhibitor

CAS:

860352-01-8 (free base)

Catalog Number:

10-4771

Activity:

Checkpoint kinase 1/2 inhibitor

Chemical Name:

3-(Carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-piperidin-3-yl]thiophene-2-carboxamide hydrochloride

Molecular Weight:

398.88

Molecular Formula:

C₁₇H₁₉FN₄O₂S • HCl

Solubility:

Soluble in DMSO (up to at least 25 mg/ml).

Physical Properties:

Yellow or brown solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°

Stability:

Stable for 1 year as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

Shipping Code:

RT

From $60.00
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BML-277 | CHK2 inhibitor

CAS:

516480-79-8

Catalog Number:

10-1024

Activity:

CHK2 inhibitor

Chemical Name:

2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide

Molecular Weight:

363.81

Molecular Formula:

C₂₀H₁₄ClN₃O₂

Solubility:

Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 20 mg/ml).

Physical Properties:

Off-white solid

Purity:

98% by TLC

NMR conforms

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $60.00
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Cantharidin | Phosphatase PP2A inhibitor

CAS:

56-25-7

Catalog Number:

10-1013

Activity:

Phosphatase PP2A inhibitor

Chemical Name:

3α,7α-Dimethylhexahydro-4,7-epoxyisobenzofuran-1,3-dione

Molecular Weight:

196.2

Molecular Formula:

C₁₀H₁₂O₄

Solubility:

Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 5 mg/ml).

Physical Properties:

White solid

Purity:

98% by TLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 weeks.

Shipping Code:

RT

From $40.00
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LY2603618 | Potent and selective Chk1 inhibitor

CAS:

911222-45-2

Catalog Number:

10-4123

Activity:

Potent and selective Chk1 inhibitor

Chemical Name:

N-[5-bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy]phenyl]-N’-(5-methyl-2-pyrazinyl)urea

Alternate Names:

Rabusertib

Molecular Weight:

436.30

Molecular Formula:

C₁₈H₂₂BrN₅O₃

Solubility:

Soluble in DMSO (up to 10 mg/ml)

Physical Properties:

Off-white solid

Purity:

98% by HPLC
NMR (Conforms)

Storage Temperature:

-20°C

Stability:

Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Shipping Code:

RT

From $50.00
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Cell Cycle Checkpoints

Adavosertib | Wee1 kinase inhibitor

AZD7762 | Checkpoint kinase 1/2 inhibitor

BML-277 | CHK2 inhibitor

Cantharidin | Phosphatase PP2A inhibitor

LY2603618 | Potent and selective Chk1 inhibitor

EXPLORE OTHER DNA Damage / Repair

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21

Cell Cycle Checkpoints

Adavosertib | Wee1 kinase inhibitor

AZD7762 | Checkpoint kinase 1/2 inhibitor

BML-277 | CHK2 inhibitor

Cantharidin | Phosphatase PP2A inhibitor

LY2603618 | Potent and selective Chk1 inhibitor

EXPLORE OTHER DNA Damage / Repair

Focus Biomolecules • Plymouth Meeting, PA USA • 1-855-FOCUS21

Focus Biomolecules Plymouth Meeting, PA USA1-855-FOCUS21

Focus Biomolecules
Plymouth Meeting, PA USA
1-855-FOCUS21