DNA Methylation
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2′-Deoxy-5-fluorocytidine | Irreversible DNA methyl transferase inhibitor
From $50.00CAS:10356-76-0Catalog Number:10-2685Activity:Irreversible DNA methyl transferase inhibitorAlternate Names:FCDR; NSC-48006; FdCydChemical Name:5-Fluoro-2’deoxycytidineMolecular Weight:245.21Molecular Formula:C9H12FN3O4Solubility:Soluble in DMSO (up to 20 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.Shipping Code:RT -
5-Azacytidine | DNA hypomethylation agent
From $20.00CAS:320-67-2Catalog Number:10-1267Activity:DNA hypomethylation agentAlternate Names:Ladakamycin; U-18496; NSC-102816; AzaCChemical Name:4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-oneMolecular Weight:244.21Molecular Formula:C8H12N4O5Solubility:Soluble in DMSO (up to 25 mg/ml), or in Water (up to 12 mg/ml).Physical Properties:White solidPurity:98% by TLC
NMR (Conforms)Storage Temperature:-20°Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.Shipping Code:RT -
6-Thioguanine | Anticancer agent / Downregulates DNMT1
From $30.00CAS:154-42-7Catalog Number:10-1282Activity:Anticancer agent / Downregulates DNMT1Chemical Name:2-Amino-6-mercaptopurineAlternate Names:6-TG; NSC 752, NSC 76504Molecular Weight:167.19Molecular Formula:C5H5N5SSolubility:Soluble in DMF (up to 1.5 mg/ml with warming)Physical Properties:Pale yellow solidPurity:96% by HPLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 1 year from date of purchase as supplied. Solutions in DMF may be stored at -20°C for up to 1 month.Shipping Code:RT -
DBIC | DNMT3B S-nitrosylation inhibitor
From $75.00DBIC (487026-67-5) specifically inhibits S-nitrosylation of DNA methyltransferase 3B (DNMT3B) at low concentrations, IC50≤100 nM, without affecting its enzymatic activity. Treatment with DBIC prevents nitric oxide-induced […]
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DBIC-neg2 | DBIC negative control
From $50.00CAS:N/ACatalog Number:10-5162Activity:DBIC negative controlChemical Names:(E)-N’-(3,4-Dihydroxybenzylidene)acetohydrazideMolecular Weight:194.19Molecular Formula:C9H10N2O3Solubility:Soluble in DMSO (40 mg/ml)Physical Properties:Pale yellow solidPurity:>98% TLC
NMR (Conforms)Storage Temperature:-20°CStability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.Shipping Code:RT
