Histone Demethylation

  • DMOG | Inhibits prolyl hydroxylase domain-containing proteins

    CAS:
    89464-63-1
    Catalog Number:
    10-2371
    Activity:
    Inhibits prolyl hydroxylase domain-containing proteins
    Alternate Names:
    Dimethyloxalylglycine
    Chemical Name:
    N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
    Molecular Weight:
    175.14
    Molecular Formula:
    C6H9NO5
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
    Physical Properties:
    Off-white solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Protect from light
    Stability:
    Stable for 2 years from date of purchase as supplied. Solutions are not stable. Solutions must be made fresh and used within 1 working day.
    Shipping Code:
    RT
    From $60.00
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  • GSK-J1 | JMJ H3K27 Demethylase inhibitor (Non-cell permeable)

    CAS:
    1373422-53-7
    Catalog Number:
    10-1393
    Activity:
    JMJ H3K27 Demethylase inhibitor (Non-cell permeable)
    Chemical Name:
    N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine
    Molecular Weight:
    389.46
    Molecular Formula:
    C22H23N5O2
    Solubility:
    Soluble in DMSO (up to 20 mg/ml).
    Physical Properties:
    Pale yellow solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    RT
    Stability:
    Stable for 2 years from date of purchase  as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $75.00
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  • GSK-J4 | JMJ H3K27 Demethylase inhibitor (Cell Permeable)

    CAS:
    1373423-53-0
    Catalog Number:
    10-1394
    Activity:
    JMJ H3K27 Demethylase inhibitor (Cell Permeable)
    Chemical Name:
    N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester
    Molecular Weight:
    417.48
    Molecular Formula:
    C24H27N5O2
    Solubility:
    Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 40 mg/ml).
    Physical Properties:
    Yellow solid
    Purity:
    99% by TLC
    NMR (Conforms)
    Storage Temperature:
    -20°
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
    Shipping Code:
    RT
    From $50.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • GSK2879552 | Potent and selective LSD1 inhibitor

    CAS:
    1401966-69-5
    Catalog Number:
    10-4020
    Activity:
    Potent and selective LSD1 inhibitor
    Chemical Name:
    4-[[4-[[[(1R,2S)-2-Phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]benzoic acid dihydrochloride
    Molecular Weight:
    437.40
    Molecular Formula:
    C23H28N2O2 • HCl
    Solubility:
    Soluble in DMSO (up to 25 mg/ml) or in Water (up to at least 25 mg/ml)
    Physical Properties:
    White solid
    Purity:
    98% by HPLC
    NMR (Conforms)
    Storage Temperature:
    -20°C
    Stability:
    Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
    Shipping Code:
    RT
    From $80.00
    View Product This product has multiple variants. The options may be chosen on the product page
  • iJMJD6 | Arginine demethylase JMJD6 inhibitor

    CAS:
    899548-78-8
    Catalog Number:
    10-4039
    View Product This product has multiple variants. The options may be chosen on the product page
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